I came to this late. Trying to catch up and digest. Your late statement is breathtaking. With every bit I understand; the more concerned I become. Weaponization of homeostasis, acceleration of disease. We see that everyday whether anecdotally or all cause mortality. Thank you for keeping on, keeping on.
Great work helping to solve the mystery of what can happen to the cleaved S2. Nothing good. And funny you mention HIF:
...Ubiquitination is described, as is evidence for the HIF inhibitory effects of both lactoferrin and ivermectin. This is important for working synergistically with doxycycline to help avoid resistance from cancer cells.
There are both cryptic sites and cryptic peptides in the S2 I already know it, I just can't find them yet.
Too much attention to the S1 because of everything there, too little everywhere else.
HIF is a double edge sword, you inhibit, you open the gates for another loop. There was way more to it, linking with a bunch of older posts buuuuuuuuuuuut, this was complex enough as it is.
Seems like TUDCA could be a potential supportive supplement given its amyloid degrating properties
"In recent years, hydrophilic bile acids, particularly tauroursodeoxycholic acid (TUDCA), have shown important anti-apoptotic and neuroprotective activities, with numerous experimental and clinical evidence suggesting their possible therapeutic use as disease-modifiers in neurodegenerative diseases. Experimental evidence on the mechanisms underlying TUDCA’s neuroprotective action derives from animal models of Alzheimer’s disease, Parkinson’s disease, Huntington’s diseases, amyotrophic lateral sclerosis (ALS) and cerebral ischemia. Preclinical studies indicate that TUDCA exerts its effects not only by regulating and inhibiting the apoptotic cascade, but also by reducing oxidative stress, protecting the mitochondria, producing an anti-neuroinflammatory action, and acting as a chemical chaperone to maintain the stability and correct folding of proteins. Furthermore, data from phase II clinical trials have shown TUDCA to be safe and a potential disease-modifier in ALS. ALS is the first neurodegenerative disease being treated with hydrophilic bile acids. "
"Consequently, a significant decrease in Aβ(1-40) and Aβ(1-42) levels was observed in both hippocampus and frontal cortex of TUDCA-treated APP/PS1 mice, suggesting that chronic feeding of TUDCA interferes with Aβ production, possibly through the regulation of lipid-metabolism mediators associated with APP processing. These results highlight TUDCA as a potential therapeutic strategy for the prevention and treatment of AD."
Will be interested to hear what you think as you read more! I find TUDCA so interesting as it seems to have some pretty amazing benefits for a number of ailments, and all it is is a bile acid. Would have never thought one thing could do so much!
The hits just keep on coming. Thanks for bringing the S2 subunit to our attention. I knew I would never take another vaccine again, but thanks for the quick answer to anyone who might pressure me in the future. The nasal cavity leads to the brain.
I will never spray any sort of protein anywhere near up my nose. Regardless of what they do with the potential pathogen, it goes directly into your brain.
And the spike from corona will literally poke roles in your BBB.
Because I am not understanding of the hard “science” this one was confusing. What I was able to glean was an AHA thought that this must be why the CCP are pushing Covid ZERO despite its destruction of their economy.
The second part of the Spike which is in the vaccines, that alone, can make your body produce a enzyme that will make more amyloid beta, the bad protein that is responsible for neurodegeneration.
This second part is unchanged in Omicron, and I left for the reader to connect the dots. With all the other posts clear where a lot of the mRNA people are going.
So, essentially, the mRNA jabbed are facing accelerated aging and disease over the next 5 to 10 years.
Those unvaccinated but infected, depending upon the type and viral load, will face a certain hit but depending upon various factors; healthy diet, immune system, viral load and age, will presumably, in general, recover quicker (apart from those who get Long Covid).
Am I right in saying the pure Omicron variant was the mildest and therefore "best" one to get of the variants. And the more recent variants are more like the older Covid variants that hammer everyone more.
Accelerated aging of the the immune system and arguably to a certain level some aspects of biological aging, yes. Your second observation also correct.
Your third, yes, all current Omicron variants are milder, with the first one being super mild, but given the mutations around the newer variants, yes they are chipping away everyone’s health to different extent the secret is giving time for the body to recover before you get reinfected. Vaccinated are in a much harder place.
I came to this late. Trying to catch up and digest. Your late statement is breathtaking. With every bit I understand; the more concerned I become. Weaponization of homeostasis, acceleration of disease. We see that everyday whether anecdotally or all cause mortality. Thank you for keeping on, keeping on.
Great work helping to solve the mystery of what can happen to the cleaved S2. Nothing good. And funny you mention HIF:
...Ubiquitination is described, as is evidence for the HIF inhibitory effects of both lactoferrin and ivermectin. This is important for working synergistically with doxycycline to help avoid resistance from cancer cells.
https://doorlesscarp953.substack.com/p/repurposing-of-the-antibiotic-doxycycline
There are both cryptic sites and cryptic peptides in the S2 I already know it, I just can't find them yet.
Too much attention to the S1 because of everything there, too little everywhere else.
HIF is a double edge sword, you inhibit, you open the gates for another loop. There was way more to it, linking with a bunch of older posts buuuuuuuuuuuut, this was complex enough as it is.
Seems like TUDCA could be a potential supportive supplement given its amyloid degrating properties
"In recent years, hydrophilic bile acids, particularly tauroursodeoxycholic acid (TUDCA), have shown important anti-apoptotic and neuroprotective activities, with numerous experimental and clinical evidence suggesting their possible therapeutic use as disease-modifiers in neurodegenerative diseases. Experimental evidence on the mechanisms underlying TUDCA’s neuroprotective action derives from animal models of Alzheimer’s disease, Parkinson’s disease, Huntington’s diseases, amyotrophic lateral sclerosis (ALS) and cerebral ischemia. Preclinical studies indicate that TUDCA exerts its effects not only by regulating and inhibiting the apoptotic cascade, but also by reducing oxidative stress, protecting the mitochondria, producing an anti-neuroinflammatory action, and acting as a chemical chaperone to maintain the stability and correct folding of proteins. Furthermore, data from phase II clinical trials have shown TUDCA to be safe and a potential disease-modifier in ALS. ALS is the first neurodegenerative disease being treated with hydrophilic bile acids. "
Full study: Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9166453/
As well: TUDCA, a Bile Acid, Attenuates Amyloid Precursor Protein Processing and Amyloid-β Deposition in APP/PS1 Mice https://www.researchgate.net/publication/221967028_TUDCA_a_Bile_Acid_Attenuates_Amyloid_Precursor_Protein_Processing_and_Amyloid-beta_Deposition_in_APPPS1_Mice
"Consequently, a significant decrease in Aβ(1-40) and Aβ(1-42) levels was observed in both hippocampus and frontal cortex of TUDCA-treated APP/PS1 mice, suggesting that chronic feeding of TUDCA interferes with Aβ production, possibly through the regulation of lipid-metabolism mediators associated with APP processing. These results highlight TUDCA as a potential therapeutic strategy for the prevention and treatment of AD."
Good find I will read more about it, funny how many supplements effectively treat or ameliorate amyloid related diseases yet you never hear about it.
Will be interested to hear what you think as you read more! I find TUDCA so interesting as it seems to have some pretty amazing benefits for a number of ailments, and all it is is a bile acid. Would have never thought one thing could do so much!
The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030606/
The hits just keep on coming. Thanks for bringing the S2 subunit to our attention. I knew I would never take another vaccine again, but thanks for the quick answer to anyone who might pressure me in the future. The nasal cavity leads to the brain.
I will never spray any sort of protein anywhere near up my nose. Regardless of what they do with the potential pathogen, it goes directly into your brain.
And the spike from corona will literally poke roles in your BBB.
Because I am not understanding of the hard “science” this one was confusing. What I was able to glean was an AHA thought that this must be why the CCP are pushing Covid ZERO despite its destruction of their economy.
The second part of the Spike which is in the vaccines, that alone, can make your body produce a enzyme that will make more amyloid beta, the bad protein that is responsible for neurodegeneration.
This second part is unchanged in Omicron, and I left for the reader to connect the dots. With all the other posts clear where a lot of the mRNA people are going.
So, essentially, the mRNA jabbed are facing accelerated aging and disease over the next 5 to 10 years.
Those unvaccinated but infected, depending upon the type and viral load, will face a certain hit but depending upon various factors; healthy diet, immune system, viral load and age, will presumably, in general, recover quicker (apart from those who get Long Covid).
Am I right in saying the pure Omicron variant was the mildest and therefore "best" one to get of the variants. And the more recent variants are more like the older Covid variants that hammer everyone more.
Accelerated aging of the the immune system and arguably to a certain level some aspects of biological aging, yes. Your second observation also correct.
Your third, yes, all current Omicron variants are milder, with the first one being super mild, but given the mutations around the newer variants, yes they are chipping away everyone’s health to different extent the secret is giving time for the body to recover before you get reinfected. Vaccinated are in a much harder place.
Thanks JP. I went out of my way to get infected with the 1st super mild omicron variant which i was successful!
Not jabbed and never infected with the worse variants.
Except the spike protein is in all the jabs.
Thank you!
I just posted a link to your article on Walter Chesnut's Substack.
Thanks again!
Careful or he will ban you from his Substack. I openly call him a grifter which he is.