This paper is also amazing and people should be aware of it. https://www.biorxiv.org/content/10.1101/2022.06.27.497883v1 - The Staphylococcus aureus iron-regulated surface determinant A (IsdA) increases SARS CoV-2 replication by modulating JAK-STAT signaling
"Using chemical inhibition, we determined S. aureus IsdA modifies host Janus Kinase – Signal Transducer and Activator of Transcription (JAK-STAT) signalling, ultimately leading to increased viral replication"
"Bacterial co-infection is a common and significant complication of respiratory viral infection,
including in patients with COVID-19, and leads to increased morbidity and mortality. The
relationship between virus, bacteria and host is largely unknown, which makes it difficult to
design effective treatment strategies. In the present study we created a model of co-infection
between SARS CoV-2 and Staphylococcus aureus, the most common species identified in
COVID-19 patients with co-infection. We demonstrate that the S. aureus protein IsdA
enhances the replication of SARS CoV-2 in vitro by modulating host cell signal transduction
pathways. The significance of this finding is in identifying a bacterial component that
enhances CoV-2 pathogenesis, which could be a target for the development of co-infection
specific therapy in the future. In addition, this protein can be used as a tool to decipher the
mechanisms by which CoV-2 manipulates the host cell, providing a better understanding of
From Twitter: "🚨 PEOPLE WITH LINGERING SARS1 SYMPTOMS GOT MORE DISABLED OVER TIME. This is why China has a zero Covid policy. They play the long game. They’re not stupid. We are."
This paper is also amazing and people should be aware of it. https://www.biorxiv.org/content/10.1101/2022.06.27.497883v1 - The Staphylococcus aureus iron-regulated surface determinant A (IsdA) increases SARS CoV-2 replication by modulating JAK-STAT signaling
"Using chemical inhibition, we determined S. aureus IsdA modifies host Janus Kinase – Signal Transducer and Activator of Transcription (JAK-STAT) signalling, ultimately leading to increased viral replication"
"Bacterial co-infection is a common and significant complication of respiratory viral infection,
including in patients with COVID-19, and leads to increased morbidity and mortality. The
relationship between virus, bacteria and host is largely unknown, which makes it difficult to
design effective treatment strategies. In the present study we created a model of co-infection
between SARS CoV-2 and Staphylococcus aureus, the most common species identified in
COVID-19 patients with co-infection. We demonstrate that the S. aureus protein IsdA
enhances the replication of SARS CoV-2 in vitro by modulating host cell signal transduction
pathways. The significance of this finding is in identifying a bacterial component that
enhances CoV-2 pathogenesis, which could be a target for the development of co-infection
specific therapy in the future. In addition, this protein can be used as a tool to decipher the
mechanisms by which CoV-2 manipulates the host cell, providing a better understanding of
COVID-19 virulence. "
Of possible interest: SARS Survivors, 10 yrs later
https://globalnews.ca/news/404562/sars-10-years-later-how-are-survivors-faring-now/
From Twitter: "🚨 PEOPLE WITH LINGERING SARS1 SYMPTOMS GOT MORE DISABLED OVER TIME. This is why China has a zero Covid policy. They play the long game. They’re not stupid. We are."
https://twitter.com/danaparish/status/1542322893723357184
I get too many notifications thank you for posting this one again. Will tweet in my Twitter.
I assume this person was also double (at least) jabbed? Might be relevant for them to mention.
Hugely appreciative of your brilliant post.... THANK YOU!