It didn't exactly fit in the article itself, but this paper is rather significant. -> Maltodextrin Consumption Impairs the Intestinal Mucus Barrier and Accelerates Colitis Through Direct Actions on the Epithelium
"These results suggest MDX disrupts the balance of epithelial cell differentiation and proliferation to contribute to disease pathogenesis through direct and indirect actions on the intestinal epithelial barrier."
I have stage 3a kidney failure. My GFR ranges from 60 to 45 on some days. It doesn't seem to matter how much fluid I drink because I always try to stay hydrated but it fluxuates often. I have come up with a standard for myself in which I figured I would drink 1/2 my body weight of fluids in ounces meaning, if I weigh 140lbs I drink 70 to 75oz of water, kombucha, tea, raw milk & juices during the day. Do you think this is sufficient amount of fluids? too much or too little? I eat organic, homegrown foods with very little purchased from the Monsanto grocery stores.
I went the local University and saw a nephrologist a year or two ago and she told me that there was nothing she could do for me to increase my kidney numbers until I get worse and then she suggested dialysis. Sick care is NOT health care. These people are educated idiots.
This is a remind to myself to get back to you tomorrow, I need to reaad some stuff on peptides.
Stage 3 is where things get very complicated, since it is now beyond compensatory mechanisms, there are other feedback loops at play too. If it is working for you and you lessen any of your symptom, doesn't matter what anyone thinks.
Thank you. I dont really have symptoms. I am not near dialysis either at this point. I DO appreciate your thoughts and comments though so please let me know what you think.
I don't recall exactly if you emailed me once, but if you did, I get so many emails there is little chance I can find it again lol, so if you want the sources for these, just email me (but google gives decent results).
These two are "expensive" but not by that much if you look for deals, and such, you need to take them for 2-3 months IF you think about going down this route.
The other two ANP and TIP, and these are what I call "specialty" peptides, they are more expensive, usually 125 to 200 dollars each vial, sometimes even more depending on the source.
I don't think I emailed you. I think I may have asked you about peptides in a substack comments section a long time ago because I am not educated about them and even though I did some reading about them, I am not sure I can find a company that I can trust since I don't know anything about peptides. I'd like to know if you happen to know of a company that sells peptides that I can trust not to have fillers or poisons? Thank you!
The vast majority of peptides come from the same source (China) it makes little to no difference where you buy, some of the companies that produced domestically in Canada and the US went under.
Anyway Peptide Sciences is used by a lot of concierge doctors, and it is very reputable.
Not sure this will help you, but I know someone who kept herself off of dialysis for a year with cranberries. She didn't go overboard, just 'some' and/ or capsules. There may be more info about this around. With so much taken down from the Internet, you might have to try a naturopath or an herbalist. Thank you for your service. Blessings.
thank you. I drink homemade cranberry juice often for that reason. No one knows how to prevent kidney failure, just how to medicate it later. I just rather drink a lot of fluids which I think helps keep things at bay
why not niacin and baking soda? there are many examples of that...they even put the case (of a doctor who wrote a chapter on the book ,how he treated his father with stage 4 ) in "Niacin the real story" second edition,,. i really think you must read the book and that chapter and treat yourself, Niacin is a mystery vitamin and its potential is still unknown.. ,but am definitely sure that combination will be useful!
What did your nephrologist recommend for blood pressure management?
As John Paul notes, stage 3 is complex. HbA1c and uric acid are important markers for risks and management as well with some connection to protein intake.
You know when something is wrong with your body you need to follow through no one else will! Watch the Pill pushers keep to natural as much as possible! Have open mind about natural healing! I have seen people told to go home write your will there is nothing we can do! I know a Joe that found out that animal dewormer kills cancer! With no side effects then used it to keep cancer away! It’s your live you must take charge if you have a doctor that does not agree get a different doctor! I have fired a Doctor in a hospital told him You Are Fired! It blew his mind but it saved my life!Stand Up for yourself and your family!
reading Guylaine Lanctot recently, a former doc who threw her title away. I also read from several people who were told to go home and die, who made changes in their lives (left straining job and got a small seaside cottage and a dog, was given a few months and they interviewed her 10 years later, on man given a year if he started treatment right away, he lived 3+ years with no treatment). Follow your gut feeling. We all will die of something. I rather eat another box of dates than live a few months longer craving them!
I have never followed advice on what and how to eat. Eat once a day, drink plenty of water and supplement. Just makes life simpler and saves on dish washing. I leave complexity to you and then you make it simpler to me. A good man is hard to find. Thank you so very much!
Oke thing I learned is that most doctors will blindly follow what an agency or organization tells it is "the truth". Evidence based medicine is also riddle with fake evidence, biased papers and manipulated data within certain subjects.
Your best strategy is the correct one, but most people lack the knowledge to properly make that call Linda (because I know you do have it :D). My wake up call was the salt one 😂 I "fixed" a lot of my teenager issues my just eating more salt 🧂.
Neither do I consider myself special, or even "smart". It is just that most people are rather...dull. For reasons beyond my mere understanding, I doubt it is just genetics, or just the enviroment. I think genetics, the enviroment, the information, language itself affect our "intelligence". But this is another one of my crazy talks.
He illuminates the difference between "consensus" medicine and "evidence-based" medicine and some of the corrupt organisations imposing their control.
For a take on manipulation of data in "peer-reviewed" medical articles, Dr. Byram Bridle on <viralimmunologist.substack.com> has a good tutorial on Sept. 26- "Let's See How Covid-19 Articles Can Be Misleading."
I think most foods are fine in moderation. I stopped eating red meat when the mad cow disease came up, and seldom eat it nowadays (but if someone cooks it for me and there is nothing else I will eat it). Recently my dog got allergic to chicken so now we are down to pork (which the doc disadvized me because it would cause infection) and turkey. Some weeks I eat 7 or 8 eggs and then I don't eat any for one or 2 weeks. Mostly I eat what I feel like eating. Nowadays I eat lots of dates, and developed a taste for honey. The doc would tell me not to, but I am not going to see him any time soon LOL
Organic honey is actually good for you (not if you are eating a lot of carbs, and honey, and bad fats) but mostly it is a powerful food =). And yes, everything is fine in moderation, but the vast majority of people (even me for half my life) lack the self-control. Sometimes the circumatances doesn't enables us to eat good, me again as a example, periods of poverty that either you eat crap, cheap carbs or you starve.
sometimes you have no choice - I have been on the road with trucking husband and we got stuck once for 3 days with nothing but mcdonalds. I will never eat it again - even when almost starving!
"Softer cuts, minced/shredded meat are easier for the gut to digest and absorb"
Wouldn't you achieve somewhat the same effect by chewing your food more? I say this as an inveterate under-chewer! I'm always having to consciously force myself to chew food more as my impulse is to swallow it too soon.
I am also a under-chewer, and this is really bad for us lol, but yes and no. Depending on the state of your microbiome and gut mucosa (such as gut inflammation) it will definitely affect the absorption even if you chew a lot. The best method is literally testing and see how the gut responds.
From a "absorption" perspective, you just need to eat enough protein, and perhaps, if needed, supplement with whatever you lack. Chewing more will DEFINITELY help though lol.
Great information. I'm already onboard the meat ship, but it's good to have specific knowledge. I'm curious of your perspective on carbohydrates during high intensity exercise. My understanding is when the body shifts to burning carbohydrates directly, consuming sugar will prevent inflammatory responses. I try to consume some protein/fat as long as possible when I'm on the bike, but eventually output will drop without sugar intake. I always find it difficult to reconcile that with my conception that sugar = poison. Should I let go of my sugar guilt and just embrace it?
In another substack I wrote that I am in favor of low carbohydrate, but that low carb for each person is very different. Some people low carb is 50 grams, but I have friends that their low carb is 250 grams 😂.
It is all related to the level of activity and the intensity of the activity itself. In general I am a fan of carb cycling, low carb for X days (5, 7, 10, up to each one) and one day of very high carb.
Carb and sugar ain't exactly bad for you if you spending the energy. The vast majority are not spending it and there is no reason to eat 500 grams of carbs per day if you are just sitting all day.
500 grams per day is 2000 calories, which is greater than sedentary maintenance for most of us. There is little room left for lipids, protein, or actual nutrients!
Olympic swimmers, rowers, and loggers doing real work can need up to 5-6000 Calories/day but the rest of us can't burn off that much food.
Question for the smart folks on here. Any significance in persistently high antibodies for spike. SARS COV 2 AB, TOTAL SPIKE readings continue to be elevated one year after infection. Wondering how to remedy this.
It didn't exactly fit in the article itself, but this paper is rather significant. -> Maltodextrin Consumption Impairs the Intestinal Mucus Barrier and Accelerates Colitis Through Direct Actions on the Epithelium
"These results suggest MDX disrupts the balance of epithelial cell differentiation and proliferation to contribute to disease pathogenesis through direct and indirect actions on the intestinal epithelial barrier."
https://www.frontiersin.org/articles/10.3389/fimmu.2022.841188/full
Here's another along the same lines: https://suppversity.blogspot.com/2015/04/no-sugar-foods-with-maltodextrin-mess.html
Damn 2015. Ahead of it's time 😎
I have stage 3a kidney failure. My GFR ranges from 60 to 45 on some days. It doesn't seem to matter how much fluid I drink because I always try to stay hydrated but it fluxuates often. I have come up with a standard for myself in which I figured I would drink 1/2 my body weight of fluids in ounces meaning, if I weigh 140lbs I drink 70 to 75oz of water, kombucha, tea, raw milk & juices during the day. Do you think this is sufficient amount of fluids? too much or too little? I eat organic, homegrown foods with very little purchased from the Monsanto grocery stores.
I went the local University and saw a nephrologist a year or two ago and she told me that there was nothing she could do for me to increase my kidney numbers until I get worse and then she suggested dialysis. Sick care is NOT health care. These people are educated idiots.
This is a remind to myself to get back to you tomorrow, I need to reaad some stuff on peptides.
Stage 3 is where things get very complicated, since it is now beyond compensatory mechanisms, there are other feedback loops at play too. If it is working for you and you lessen any of your symptom, doesn't matter what anyone thinks.
Thank you. I dont really have symptoms. I am not near dialysis either at this point. I DO appreciate your thoughts and comments though so please let me know what you think.
thanks
I don't recall exactly if you emailed me once, but if you did, I get so many emails there is little chance I can find it again lol, so if you want the sources for these, just email me (but google gives decent results).
I spend a couple hours reading and researching, and as I suspect there are peptides that are nephroprotective, and can stop or outright "reverse" disease, but there isn't a lot of published cases let alone trials. Anyway, as usual the most common "combo" is BPC-157 and Thymosin Beta-4 -> Here are two cases and a good reading https://thespiritoflivefood.com/2021/07/03/peptide-bpc-157-demonstrates-healing-effect-on-end-stage-kidney-disease/
These two are "expensive" but not by that much if you look for deals, and such, you need to take them for 2-3 months IF you think about going down this route.
The other two ANP and TIP, and these are what I call "specialty" peptides, they are more expensive, usually 125 to 200 dollars each vial, sometimes even more depending on the source.
Best regards.
I don't think I emailed you. I think I may have asked you about peptides in a substack comments section a long time ago because I am not educated about them and even though I did some reading about them, I am not sure I can find a company that I can trust since I don't know anything about peptides. I'd like to know if you happen to know of a company that sells peptides that I can trust not to have fillers or poisons? Thank you!
The vast majority of peptides come from the same source (China) it makes little to no difference where you buy, some of the companies that produced domestically in Canada and the US went under.
Anyway Peptide Sciences is used by a lot of concierge doctors, and it is very reputable.
Not sure this will help you, but I know someone who kept herself off of dialysis for a year with cranberries. She didn't go overboard, just 'some' and/ or capsules. There may be more info about this around. With so much taken down from the Internet, you might have to try a naturopath or an herbalist. Thank you for your service. Blessings.
thank you. I drink homemade cranberry juice often for that reason. No one knows how to prevent kidney failure, just how to medicate it later. I just rather drink a lot of fluids which I think helps keep things at bay
why not niacin and baking soda? there are many examples of that...they even put the case (of a doctor who wrote a chapter on the book ,how he treated his father with stage 4 ) in "Niacin the real story" second edition,,. i really think you must read the book and that chapter and treat yourself, Niacin is a mystery vitamin and its potential is still unknown.. ,but am definitely sure that combination will be useful!
Thank you Sky! Ill check it out.
What did your nephrologist recommend for blood pressure management?
As John Paul notes, stage 3 is complex. HbA1c and uric acid are important markers for risks and management as well with some connection to protein intake.
I dont have any heart or blood pressure issues which I know usually go along with kidney failure.
You know when something is wrong with your body you need to follow through no one else will! Watch the Pill pushers keep to natural as much as possible! Have open mind about natural healing! I have seen people told to go home write your will there is nothing we can do! I know a Joe that found out that animal dewormer kills cancer! With no side effects then used it to keep cancer away! It’s your live you must take charge if you have a doctor that does not agree get a different doctor! I have fired a Doctor in a hospital told him You Are Fired! It blew his mind but it saved my life!Stand Up for yourself and your family!
reading Guylaine Lanctot recently, a former doc who threw her title away. I also read from several people who were told to go home and die, who made changes in their lives (left straining job and got a small seaside cottage and a dog, was given a few months and they interviewed her 10 years later, on man given a year if he started treatment right away, he lived 3+ years with no treatment). Follow your gut feeling. We all will die of something. I rather eat another box of dates than live a few months longer craving them!
I have never followed advice on what and how to eat. Eat once a day, drink plenty of water and supplement. Just makes life simpler and saves on dish washing. I leave complexity to you and then you make it simpler to me. A good man is hard to find. Thank you so very much!
It took me a lot of pain, suffering and for a short time utter misery to learn "just do the opposite of what doctors tell you to do".
At least all that it servesd a purpose.
The caveat is doctors keep changing their collective minds. My best strategy is be mindful; don’t blindly eat, sleep, exercise, etc.
Oke thing I learned is that most doctors will blindly follow what an agency or organization tells it is "the truth". Evidence based medicine is also riddle with fake evidence, biased papers and manipulated data within certain subjects.
Your best strategy is the correct one, but most people lack the knowledge to properly make that call Linda (because I know you do have it :D). My wake up call was the salt one 😂 I "fixed" a lot of my teenager issues my just eating more salt 🧂.
Thank you. However your observation makes me sad. I don’t consider myself special.
Neither do I consider myself special, or even "smart". It is just that most people are rather...dull. For reasons beyond my mere understanding, I doubt it is just genetics, or just the enviroment. I think genetics, the enviroment, the information, language itself affect our "intelligence". But this is another one of my crazy talks.
you are special just because you are a doctor on substack. thank you for being with us.
Thank you for the high praise. I don’t want to misrepresent myself, I am a simple PhD. I opted out of med school. Still Dr though. : )
Have a look at <amidwesterndoctor.substack.com> from Aug.22- What happens to Doctors Who Innovate?
He illuminates the difference between "consensus" medicine and "evidence-based" medicine and some of the corrupt organisations imposing their control.
For a take on manipulation of data in "peer-reviewed" medical articles, Dr. Byram Bridle on <viralimmunologist.substack.com> has a good tutorial on Sept. 26- "Let's See How Covid-19 Articles Can Be Misleading."
I think most foods are fine in moderation. I stopped eating red meat when the mad cow disease came up, and seldom eat it nowadays (but if someone cooks it for me and there is nothing else I will eat it). Recently my dog got allergic to chicken so now we are down to pork (which the doc disadvized me because it would cause infection) and turkey. Some weeks I eat 7 or 8 eggs and then I don't eat any for one or 2 weeks. Mostly I eat what I feel like eating. Nowadays I eat lots of dates, and developed a taste for honey. The doc would tell me not to, but I am not going to see him any time soon LOL
Organic honey is actually good for you (not if you are eating a lot of carbs, and honey, and bad fats) but mostly it is a powerful food =). And yes, everything is fine in moderation, but the vast majority of people (even me for half my life) lack the self-control. Sometimes the circumatances doesn't enables us to eat good, me again as a example, periods of poverty that either you eat crap, cheap carbs or you starve.
sometimes you have no choice - I have been on the road with trucking husband and we got stuck once for 3 days with nothing but mcdonalds. I will never eat it again - even when almost starving!
I am with you about most doctors! Very few want to heal you most just practice on you and just give bandaid approach!
Good man!
"Softer cuts, minced/shredded meat are easier for the gut to digest and absorb"
Wouldn't you achieve somewhat the same effect by chewing your food more? I say this as an inveterate under-chewer! I'm always having to consciously force myself to chew food more as my impulse is to swallow it too soon.
I am also a under-chewer, and this is really bad for us lol, but yes and no. Depending on the state of your microbiome and gut mucosa (such as gut inflammation) it will definitely affect the absorption even if you chew a lot. The best method is literally testing and see how the gut responds.
From a "absorption" perspective, you just need to eat enough protein, and perhaps, if needed, supplement with whatever you lack. Chewing more will DEFINITELY help though lol.
I found this post extremely informative. Thanks
Great information. I'm already onboard the meat ship, but it's good to have specific knowledge. I'm curious of your perspective on carbohydrates during high intensity exercise. My understanding is when the body shifts to burning carbohydrates directly, consuming sugar will prevent inflammatory responses. I try to consume some protein/fat as long as possible when I'm on the bike, but eventually output will drop without sugar intake. I always find it difficult to reconcile that with my conception that sugar = poison. Should I let go of my sugar guilt and just embrace it?
In another substack I wrote that I am in favor of low carbohydrate, but that low carb for each person is very different. Some people low carb is 50 grams, but I have friends that their low carb is 250 grams 😂.
It is all related to the level of activity and the intensity of the activity itself. In general I am a fan of carb cycling, low carb for X days (5, 7, 10, up to each one) and one day of very high carb.
Carb and sugar ain't exactly bad for you if you spending the energy. The vast majority are not spending it and there is no reason to eat 500 grams of carbs per day if you are just sitting all day.
500 grams per day is 2000 calories, which is greater than sedentary maintenance for most of us. There is little room left for lipids, protein, or actual nutrients!
Olympic swimmers, rowers, and loggers doing real work can need up to 5-6000 Calories/day but the rest of us can't burn off that much food.
Question for the smart folks on here. Any significance in persistently high antibodies for spike. SARS COV 2 AB, TOTAL SPIKE readings continue to be elevated one year after infection. Wondering how to remedy this.
Unless you have symptoms or Long COVID, just means you have areong, long lasting antibodies, happens to a few people sometimes.
If symptoms present, means you may have a part of the virus sticking around
Antibodies naturally wane (vanish) overtime.