To say I am “over my skis” is an understatement, but here goes. Are these non-canonical proteins activated/dependent on the Quasi swarm, individual genetics or is it just viral Russian roulette? Not that any of these are any better than the other.
Individual genetics, individual response of each immune system. Mutations might change or outright delete these effects, since they are not… natural per se, in this specific case.
I just re-read your post, and after reading Dr. Syed's post discussing PRRARSV, I can now apprehend why in the authors' summary the PRRARSC may supersede the importance of the furin cleavage site and act as a novel pathogenic feature of SARS2.
Do you think that the furin cleavage site is merely promoting entrance of the spike into the cell, while this novel HIV insert site facilitates nuclear translocation?
It is dual use. Host expression of furin or some structural sequence yet to be identified must control when it cleaves, and when it translocate to the nucleus. At the end they didn’t find that much in the nucleus but it is important nonetheless.
I put out a post on this looking at PRRAR as a descendent of HIV-1 Tat research, which has been going on for decades. Tat is favored in lab work because it breaks through protective barriers and heads for the nucleus.
It has therefore long been used for gene delivery as well as in vaccine-attempt research, including HIV vaccine.
It is also known to cause brain damage and syncytia-building, which (along with its disruption of the extracellular matrix e.g. MMPs etc.) could explain the giant white clots and sudden death via brain stem or heart syncytia - the former has long been shown via Tat, the latter has been histologically found in heart of recent sudden death.
They don’t know, and sometimes they find something but they don’t connect the dots, or connect and don’t write to avoid the massive list of academic problems soon to follow.
Arguably a lot of my COVID stuff is about the inserts I just avoid naming them for multiple purposes.
The most meaningful and pertinent one (Insert 3) naturally occurs in some coronaviruses too. This is the galectin fold.
The hairpin and the others are all unnatural and multifunctional. I have yet to understand how or why such small amino acid sequences can have so many functions.
if you look into protein digestion, Spike included (difficult though due to the PP dipeptides) and realize that this entire process has to be completed all the way down to the single amino acids, and those are essential in neurotransmission, then the fact that all these tiny pieces do play a role is easier to grasp. On other note fragments as small as 14 amino acids are determining the anti-body production, and with such a huge colosseum like Spike with 1273 aa's you have countless choices. What was so questionable for me was the C-terminal fragment of the Spike, that Cys-rich section, patented almost from very begin of coronaviruses, preserved totally in SARS-CoV-2... Dr. Ardis helped me with that, it appears it is homolog to many venom toxins...
I do understand the role of the amino acid sequences and peptides, what I don't how a sequence of 6 amino acid can have 5 different functions. Than another 6 has 2 perhaps 3 know functions.
Than we have the FCS (8 AA) that has 3 or 4 known functions.
For last, we have another 8, that plays 2 known function potentially 3.
Excluding the fact that they may play a covert role of molecular clamps. They all may play a role on receptor binding, plus each new "novel" function.
The sequence and all the different properties of every single amino acid is the answer, in my opinion. Aromatics will absorb and emit light, charged one deliver currents, some like water, some don't. Depending what conditions the peptide is in (physico-chemical) so will be their reaction. And on top of it DNA/RNA does it all in the same time, it does optics and eletrodynamics simultaneously, to say the least. The smaller it gets the more flexible things can get. Your list from above is possibly not even 1% of all the other functions the pieces can have. That's why every single aa, di-peptide, tri-petide, etc., counts. And that's why the entire synthetic mimicry is so detrimental to the natural world.
If you go in my Twitter you will see I never gave much thought besides “are these inserts functional “. Not only they are, but they play a large role in the long-term damage of the virus.
It's entirely possible that HIV isn't nearly as deadly as propagandized (lifestyle IMO has about 98% of the blame IMO), and as you state, criminal psychopaths like Fauci have used it to aggrandize and enrich themselves.
That said, it's also entirely possible that the psychopathic genociders that are currently in "control" believe their own bullshit, and have engineered C19 to contain all sorts of things they believe are lethal.
As usual, it's "this AND that" not "this OR that"...
To say I am “over my skis” is an understatement, but here goes. Are these non-canonical proteins activated/dependent on the Quasi swarm, individual genetics or is it just viral Russian roulette? Not that any of these are any better than the other.
Individual genetics, individual response of each immune system. Mutations might change or outright delete these effects, since they are not… natural per se, in this specific case.
Thank you!
I just re-read your post, and after reading Dr. Syed's post discussing PRRARSV, I can now apprehend why in the authors' summary the PRRARSC may supersede the importance of the furin cleavage site and act as a novel pathogenic feature of SARS2.
Do you think that the furin cleavage site is merely promoting entrance of the spike into the cell, while this novel HIV insert site facilitates nuclear translocation?
Am I all wrong?
Thank you to all the kind, brainy people!
.
It is dual use. Host expression of furin or some structural sequence yet to be identified must control when it cleaves, and when it translocate to the nucleus. At the end they didn’t find that much in the nucleus but it is important nonetheless.
Therefore, you are not wrong.
I put out a post on this looking at PRRAR as a descendent of HIV-1 Tat research, which has been going on for decades. Tat is favored in lab work because it breaks through protective barriers and heads for the nucleus.
It has therefore long been used for gene delivery as well as in vaccine-attempt research, including HIV vaccine.
It is also known to cause brain damage and syncytia-building, which (along with its disruption of the extracellular matrix e.g. MMPs etc.) could explain the giant white clots and sudden death via brain stem or heart syncytia - the former has long been shown via Tat, the latter has been histologically found in heart of recent sudden death.
https://medquotes.substack.com/p/not-new-arginine-hiv-tat-lab-tool
Thank you for your kind reply.
Really, really nice of you!!
Wow, more HIV inserts. 😵💫 Crazy that it's not accepted or known. People studying it must know of course, but the general public doesn't seem to.
They don’t know, and sometimes they find something but they don’t connect the dots, or connect and don’t write to avoid the massive list of academic problems soon to follow.
a summary from last year touches lot of the pieces in the Spike, 100% proof:
https://mejbcart.substack.com/p/how-much-hiv-is-in-sars-cov-2-faucis
Arguably a lot of my COVID stuff is about the inserts I just avoid naming them for multiple purposes.
The most meaningful and pertinent one (Insert 3) naturally occurs in some coronaviruses too. This is the galectin fold.
The hairpin and the others are all unnatural and multifunctional. I have yet to understand how or why such small amino acid sequences can have so many functions.
if you look into protein digestion, Spike included (difficult though due to the PP dipeptides) and realize that this entire process has to be completed all the way down to the single amino acids, and those are essential in neurotransmission, then the fact that all these tiny pieces do play a role is easier to grasp. On other note fragments as small as 14 amino acids are determining the anti-body production, and with such a huge colosseum like Spike with 1273 aa's you have countless choices. What was so questionable for me was the C-terminal fragment of the Spike, that Cys-rich section, patented almost from very begin of coronaviruses, preserved totally in SARS-CoV-2... Dr. Ardis helped me with that, it appears it is homolog to many venom toxins...
I do understand the role of the amino acid sequences and peptides, what I don't how a sequence of 6 amino acid can have 5 different functions. Than another 6 has 2 perhaps 3 know functions.
Than we have the FCS (8 AA) that has 3 or 4 known functions.
For last, we have another 8, that plays 2 known function potentially 3.
Excluding the fact that they may play a covert role of molecular clamps. They all may play a role on receptor binding, plus each new "novel" function.
The sequence and all the different properties of every single amino acid is the answer, in my opinion. Aromatics will absorb and emit light, charged one deliver currents, some like water, some don't. Depending what conditions the peptide is in (physico-chemical) so will be their reaction. And on top of it DNA/RNA does it all in the same time, it does optics and eletrodynamics simultaneously, to say the least. The smaller it gets the more flexible things can get. Your list from above is possibly not even 1% of all the other functions the pieces can have. That's why every single aa, di-peptide, tri-petide, etc., counts. And that's why the entire synthetic mimicry is so detrimental to the natural world.
I think people give too much thought to HIV and crooks like Gallo and Fauci have lied about it.
If you go in my Twitter you will see I never gave much thought besides “are these inserts functional “. Not only they are, but they play a large role in the long-term damage of the virus.
It's entirely possible that HIV isn't nearly as deadly as propagandized (lifestyle IMO has about 98% of the blame IMO), and as you state, criminal psychopaths like Fauci have used it to aggrandize and enrich themselves.
That said, it's also entirely possible that the psychopathic genociders that are currently in "control" believe their own bullshit, and have engineered C19 to contain all sorts of things they believe are lethal.
As usual, it's "this AND that" not "this OR that"...
-=-
Covid 19 vaccine damage repair protocols:
https://davenarby.substack.com/p/covid-19-vaccine-damage-repair-protocol