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Carrie's avatar

Your background is absolutely fascinating! Thanks for this enlightening piece. I learned several things from it.

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Ashley guillot's avatar

Amazing! I can testify that what your saying works. I had brain fog and couldn’t smell after Covid. I tried water fasting 6 days for autophagy, then the FLCCC protocol (including ivermectin) and neither seemed to help. Then I read about dmitry kats flush niacin protocol (including NAC, flush niacin, and other vitamins/supplements) and my symptoms pretty much resolved. I also drink Coke Zero everyday. I’m not sure If it was the combo or maybe the post viral syndrome resolved after 9 months. My PCP told me to stop aspartame because it causes migraines and gave him atrial fib, but I just can’t give it up. Had no clue that aspartame was a calcium channel blocker, makes sense that it can induce arrhythmias. Thank you for all your research. ❤️

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Moriarty's avatar

I firmly believe Coke Zero helped, it helps NAC work better too, it is just with Piracetam it supercharges everything.

It is a fairly mild calcium blocker though, arrhythmias from aspartame would need over 1.5 Liters of Coke Zero I think, and only a very small percentage of people.

Glad you are finally free of the after effects.

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Kirsten's avatar

Thanks for sharing your background, good for you. 👍🏼💕

I'm going to try your brain stack. I don't feel like I have brain fog, but due to a couple young traumatic experiences, I feel like my brain is disorganized, and sometimes I have word finding difficulties. I've bought everything so it's on its way, I'll let you know how it goes. 🌷

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Moriarty's avatar

I shared because without it, wouldn't make any sense, it would feel like I am taking things out of thin air lol, when in fact I use myself as a test subject most of the time haha.

Trauma can be hard, I found my own way to deal with mine, but it ain't for everybody, and the stack will help with both with making sense of the trauma, putting in the past so to speak, and with the disorganized, and difficulty absolutely will. =)

I hope it helps you to any degree !

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Kirsten's avatar

Thank you! 😘

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SG_observer's avatar

Need your input on this. I just ordered Coke Zero locally (in Singapore) and the sweetener used is ACESULFAME POTASSIUM instead of aspartame. Chemical compound quite different. I've had to use Amazon to get EQUAL packets from overseas... Should Coke Zero still be a critical compound for the stack, or I mix up a drink with 1 Equal packet instead? or Make the Coke Zero super sweet with EQUAL? *yikes*

Kindly please advise. Thanks. I think they switched away from Aspartame as it has calories... aka the low-calories fad is still ongoing.

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Moriarty's avatar

Forgot to add, I also need to add on the article itself, or send a e-mail.

If you don't have a high protein diet, or eat enough eggs, you MUST add choline (supplement) to your diet. It is what Piracetam uses to do what it does.

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Moriarty's avatar

Bro sorry taking so much time to reply, I legit thought I was hacked lol your e-mail notification kept vanishing from my inbox. To the crux of the matter.

I thought that the use of that particular sweetener (aspartame) would be standardized, but I guess regulation + costs would affect that. So, I tested the "stack" with different Sodas, and Coke is the only one that worked, my guess is the aspartame+caffeine+ something else we are not aware of is doing the compounding effect.

You may try without the Coke Zero and see the results, then try it with it. I think adding aspartame to Coke Zero would make unbearably sweet, perhaps take one 15 minutes before the other. Like take the aspartame with something else. Than stack+coke zero, would make it "normal".

There is some politics/med stuff behind aspartame, I guess some countries will shy away or make the use of it at industrial scale expensive enough to discourage the use. I hope the stack bring the benefits many get. Have a great week.

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SG_observer's avatar

So I've finally managed to get my Piracetam (from India) released by the local health authorities that intercepted it. It's not illegal here, but I think they were on the lookout for any drug packages from India with regards to IVM.

Anyways, it's the 2nd night I've tried the combo with dinner. I take benotiamine with thiamine earlier in the afternoon... 800mg of Pira. 3+ hrs later, I start breaking out in hives... ears start burning. I'm using Benadryl to control the allergic reaction. Bummer that it doesn't seem to work for me... or maybe the Piracetam I got is contaminated during the manufacturing process. I bought 2 versions of it though, might give the other one a try.. though I don't want to push my luck too much with the allergic reaction.

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Moriarty's avatar

Don't push your luck, that is a actual allergic reaction to it I never ever heard of it, but it can happen.

Unless you took Niacin with it 🤔which I don't think you did.

Is your purpose for using Piracetam for brain regeneration ?

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SG_observer's avatar

Yes, taking Niacin with it.. suggested max dose. I'm adding the aspartame to the coke zero - maybe that's causing the reaction... will experiment without the aspartame as someone else has mentioned hives reaction to that. I also have 2 versions of Piracetam... both from India, so that's the next thing to try, changeover to the other version.

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Moriarty's avatar

I am close to a 90% sure it was the Niacin and not the Piracetam. What you felt on your ears, the burning sensation is classic Niacin Flush.

Try taking things without Niacin.

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SG_observer's avatar

Reporting back.. yes it was the Niacin flush, but it only occurred 3 hours later - on the mark and lasted for 45min to 1 hr. I have 2 kids on the protocol and maybe once a week they get the flush in a minor way. My flush is now a lot less noticeable after 1 week of trialling it.

My concern now is with the coke zero + aspartime.. basically I'm taking 2 kinds of artificial sweeteners - and that can't be good for my gutbiome and some newer readings confirm it. Is this a daily routine for you or on and off? I think my brain function is pretty optimized, after 2 weeks of treatment, I can make say, 2.5 intuitive leaps vs 2 before.. so nothing significant for me. I was actually hoping to improve my eyesight actually... so may have to up the dosage to 4g like you said.. how long before I could see some results? Thanks.

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Ali Beebs's avatar

Still exploring this Olive Leaf thing :) Let me know if you think it's promising.

https://scienceofparkinsons.com/2017/06/01/oleuropein-surely-the-richest-gift-of-heaven/

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Moriarty's avatar

It is a very good supplement, but here it is too shady to source, I don't trust brazilian supplier, high likelihood of tainted product. If you live in the first world, it is a no brainer.

There are many supplements that people should try, but a lot of those I don't have access (I mostly recommend things I tested myself).

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Janiesaysyay's avatar

This is a harrowing story. So glad you are alive JP! Good that you could hear the doctor and make the changes to be healthy.

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Moriarty's avatar

Thank you. I shared this so people understand where I am coming from, not taking things out of thin air, I often use myself as a test subject.

I listened just a few parts of what he said, it laid the groundwork for my thought process. Besides "Change or die", he also told me "Don't trust anything any doctor tells you, even me, verify it yourself. Take charge of your own decisions, not many can do it, you can."

Best advice ever.

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Jen Hildreth's avatar

As someone who has struggled with ADHD my entire life, I find this article fascinating. I have two questions: where do your source your piracetam? And what ingredient in Coke Zero enhances the synergy between the niacin, NAC and piracetam? I am highly sensitive to aspartame (induces migraine) and can't have it. Thanks!

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Moriarty's avatar

Locally, here we have something similar to Compounding Pharmacies, but here we call it Manipulation Pharmacies, they synthetize a lot of things. It is way cheaper, and the place I buy the quality is really good.

It is arpartame. You might try other calcium blockers, but I think there are other things inside Coke Zero that does this, because I tried other carbonated drinks, it only works with Coke Zero.

It will work without it, but it won't have this absurd enhancing effect. Perhaps the entire stack will keep the migraine at bay ?

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Carrie's avatar

I can’t tolerate any artificial sweeteners at or or even things like stevia. So I had the same question.

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Moriarty's avatar

Don't know if Substack sends a notification when I reply to one comment in a column, but here is what I replied to Jen.

Locally, here we have something similar to Compounding Pharmacies, but here we call it Manipulation Pharmacies, they synthetize a lot of things. It is way cheaper, and the place I buy the quality is really good.

It is arpartame. You might try other calcium blockers, but I think there are other things inside Coke Zero that does this, because I tried other carbonated drinks, it only works with Coke Zero.

It will work without it, but it won't have this absurd enhancing effect. Perhaps the entire stack will keep the migraine at bay ?

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Johnny B Goode's avatar

Doesn't seem to be an easy way or place to buu piracetam

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Moriarty's avatar

I have found two websites that have them. I am not affiliated, never used them, just found online.

https://newmind.com/piracetam.html -> Powder

https://nootropicsource.com/shop/capsules/piracetam-capsules/ -> Capsules

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Susan's avatar

Thanks! The first company has a requirement that the buyer be accredited -- I think they mean you must have a plan to use it in research. the second one only accepts crypto for payment if you are outside the USA. I find this fascinating! First time I have encountered this.

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Moriarty's avatar

Some countries have issues with Piracetam distribution, but almost everywhere you can import it, and it is not expensive, it is super cheap.

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Ali Beebs's avatar

Good sir, at the risk of seeming an ingrate for this wonderous post, what is the component of Coke Zero that makes it a mild calcium channel blocker, and/or what is a natural alternative? Thank you for your generosity. My only complaint is that you apologize far to often! We love your work, please don't apologize for posting as often as you like. We enjoy your beautiful brain musings!

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989080/

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Moriarty's avatar

No. It is the sweetener Aspartame. Maybe other mild calcium blockers would work. You can try without it too, it will work, just not to the extent that I wrote it here.

There is another mild calcium blocker used in research but it is impossible to buy.

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skylover's avatar

Thank you so much for this informative post! definitely will try this stack out.. as i am regular flush Niacin user, 750mg or 1g of Niacin along with this combo will work too i guess? anyway will try 500mg first time!

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MOMinator's avatar

Do you recommend a particular manufacturer/brand of the supplements here?

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Moriarty's avatar

No, 90%+ of the Piracetam in the world comes from China and India, literally doesn't matter. Maybe read the reviews of brands you think are better, that might be a indicator.

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MOMinator's avatar

Thanks!

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Butterfly2510's avatar

Hi. Thank you for this great article. I started on this but with no Coke Zero. I didn’t see any changes that I can speak of but I’m not giving up. I don’t drink coke but I will try it for a month. How much choline? I don’t eat a lot of protein.

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SG_observer's avatar

Hi, it looks like I'll be trying this with dinner as my main meal. But normally I would have a couple glasses of wine with food - so what has been your experience of the brain stack + alcohol? Thanks.

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DoorlessCarp🐭's avatar

It is enlightening, will add this to my references. 5-10mg piperine or 200mg+ silymarin is also great to add to some stacks to massively increase bioavailability. Various researchers investigated and published.

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Moriarty's avatar

Most of the time I recommend stuff I test myself for weeks/months. I don't have access to Silymarin (hard to find, obscenely expensive when I find it). Piperine it is rather easy to find but never tested.

Piracetam does other things too. The best one is affecting cell and mitochondria permeability, so the other stuff in the stack enter the cells and the mitochondria, it is what makes things go brrrr, in a way.

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DoorlessCarp🐭's avatar

I'm intrigued by transfection mediated multidrug resistance due to elevated cytoplasmic ROS, which complicates chemotherapy to treat tumors created by the same thing. Efflux pumps protect the cell from the ACE2 / NF-kB oxidative pathways assault.

First thing they do is boost cancer patients, suppress their p53 and inhibit their therapies. It's like Dark Ages quackery, or is it just me?

Btw milk thistle) silymarin & berberine are excellent for reversing MDR as well as multi factor tumor inhibition.

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