Tomorrow or the day after I will send two short e-mails, but you may add your input here in any case.
It is clear by now SARS-CoV "frenzy" is coming to a end, and while I have "freedom" to write what I want for the most part, mostly my focus was (still is at a personal level) SARS-CoV-2.
Readers should give input on which direction to take this Substack. I still have a lot planned to write, and still a lot to write as an FYI.
". . . There is the avenue of inflammatory markers, but I found this one too much “hit or miss” for people who are 1, 2, or even 3 years battling Long Covid, . . . "
My experience may be of interest to some: four weeks post onset of getting COVID, I had my blood drawn at LabCorp and tested for CRP and serum ferritin. The CRP was about 74 (should be under 3!) and the ferritin was 3½ times the upper limit of normal. Nine months later I re-tested, and my CRP was about 1, and the serum ferritin had returned to normal also. Such is the inflammatory potential of COVID!!! YIKES!
And that was in spite of super high serum vitamin D, and taking several grams per day of vitamin C, prior to and during the COVID infection.
There was a case study published reporting complete resolution of COVID in about two days with the use of 23mg oral zinc lozenges every two or three hours totalling about 200 mg over 24 hours! 200 mg! One would not want to keep that up very long, and zinc lozenges have been known to have a deleterious effect on taste buds, but perhaps over a longer period of exposure. Also, I am wondering how much of it was absorbed sublingually? Interesting, but many questions. However, zinc is a powerful antiviral for some types. If one had a very serious viral infection, it would be worth considering.
Thanks. can say Chinese skullcap seemed to help me. Seemed because as always these things are hard to feret out exactly. but WAY stronger than Quercetin
There are many mushrooms that work, I just decided to write this from basically my annotations and result with some Long COVID people (plus input of said friend). I find quercetin lacking most of the times and personally prefer Fisetin
Hi, in the high-dose stack you mention specifically Pyrodoxine (PN), and not (just any) B6. Is that an intentional preference of PN over other B6 forms?
Further, for C-Salts, would Sodium Ascorbate qualify as a C-Salt?
Lastly, about Quercetin, do you have an opinion on Quercetin Phytosome?
Evidence is contradictory most of the time. Yes it is cancer fuel, but it is also immune modulatory. Berberine/Metformin would theoretically offset sole of the risks.
I think it would have reached statistical significance but at researchers can't just put a bunch of confounders using high dosages otherwise paper wouldn't get published.
Worth a try, but I would add either a mushroom or something that directly affects either the immune system, or the metabolism.
Tomorrow or the day after I will send two short e-mails, but you may add your input here in any case.
It is clear by now SARS-CoV "frenzy" is coming to a end, and while I have "freedom" to write what I want for the most part, mostly my focus was (still is at a personal level) SARS-CoV-2.
Readers should give input on which direction to take this Substack. I still have a lot planned to write, and still a lot to write as an FYI.
Take care of your health. Best regards.
". . . There is the avenue of inflammatory markers, but I found this one too much “hit or miss” for people who are 1, 2, or even 3 years battling Long Covid, . . . "
My experience may be of interest to some: four weeks post onset of getting COVID, I had my blood drawn at LabCorp and tested for CRP and serum ferritin. The CRP was about 74 (should be under 3!) and the ferritin was 3½ times the upper limit of normal. Nine months later I re-tested, and my CRP was about 1, and the serum ferritin had returned to normal also. Such is the inflammatory potential of COVID!!! YIKES!
And that was in spite of super high serum vitamin D, and taking several grams per day of vitamin C, prior to and during the COVID infection.
excellent post! please continue your substack on what you are writing for last few years....
I will !!!
There was a case study published reporting complete resolution of COVID in about two days with the use of 23mg oral zinc lozenges every two or three hours totalling about 200 mg over 24 hours! 200 mg! One would not want to keep that up very long, and zinc lozenges have been known to have a deleterious effect on taste buds, but perhaps over a longer period of exposure. Also, I am wondering how much of it was absorbed sublingually? Interesting, but many questions. However, zinc is a powerful antiviral for some types. If one had a very serious viral infection, it would be worth considering.
Thanks. can say Chinese skullcap seemed to help me. Seemed because as always these things are hard to feret out exactly. but WAY stronger than Quercetin
There are many mushrooms that work, I just decided to write this from basically my annotations and result with some Long COVID people (plus input of said friend). I find quercetin lacking most of the times and personally prefer Fisetin
Although this one quite pricey
Yep skullcap cheap and relaxing herb.
Hi, in the high-dose stack you mention specifically Pyrodoxine (PN), and not (just any) B6. Is that an intentional preference of PN over other B6 forms?
Further, for C-Salts, would Sodium Ascorbate qualify as a C-Salt?
Lastly, about Quercetin, do you have an opinion on Quercetin Phytosome?
Yes most papers use Pyridoxine, specifically.
Somewhat similar. But doesn't qualify as C salts, if you can't find or have access to C salts, stick to liposomal.
No strong opinion, it price difference is minimal, buy it, if big stick to the quercetin most use.
Thanks for always taking the time to reply!
No problem. Hope you recover fast if you are trying to recover from something =).
For thiamine, the Benfotiamine is supposedly better absorbed.
Methylcobolamine is the superior form of B12.
And some people don't utilize regular folic acid well and do better with methylfolate.
"Doris Loh is one of the world’s leading experts on Melatonin and Vitamin, and I highly recommend you check out her work."
Should read: "vitamin C", right?
Yes. I will make any corrections tomorrow, or the day after. Most of my readers can piece things together even without corrections.
Of course! I'm just a little "perfectionistic". Sometimes.
"Metformin controls Herpes Simplex and induces immunoinflammatory lesions . . . "
Did you mean REduces???
"Herpesviruses, but especially Vitamin D are known to be able to directly block Vitamin D receptors . . . "
Uh . . . what???
One of many many papers https://www.tandfonline.com/doi/full/10.1586/ern.11.97#:~:text=The%20Epstein%E2%80%93Barr%20virus%20protein,growth%20arrest%20and%2For%20apoptosis.
https://pubmed.ncbi.nlm.nih.gov/20593215/
It goes on and gets more complicated.
Glutamine is fuel for cancer (besides glucose). With the cancer potential from these viruses, perhaps it should be approached with caution.
Evidence is contradictory most of the time. Yes it is cancer fuel, but it is also immune modulatory. Berberine/Metformin would theoretically offset sole of the risks.
Contextual, but caution is good always.
"HHV6 DNA copy numbers tended to be decreased by treatment but without reaching statistical significance.”
"The nutritional drink was 50 ml of liquid containing 10 mg vitamin B1, 1.8 mg vitamin B2, 15 mg niacin, 10 mg vitamin B6, 30 μg vitamin B12, 0.5 mg folic acid, 60 mg vitamin C, 500 mg carnitine, 30 mg coenzyme Q10 (CoQ10), 5 g naïve galacto-oligosaccharide, and 8 mg zinc".
8 MG ZINC : what might have the antiviral effect been with 40 mg zinc, or 20 mg TID?
And likewise: if higher levels of the B vitamins, vitamin C, and carnitine had been used?
I think it would have reached statistical significance but at researchers can't just put a bunch of confounders using high dosages otherwise paper wouldn't get published.
Worth a try, but I would add either a mushroom or something that directly affects either the immune system, or the metabolism.