Thank you! Thank you! Thank you! I love when you write the way you do! I remember you said that sometimes you take up to 30mg Melatonin. How do you decide when you will take 30mg or less.? Does it go by height/weight ratio.? Also, i read that metaformin has some toxicity and that berberine might be better although they work slightly differently..what do you think? Can we use berberine and/or metaformin interchangeably or just metformin?
I have a very specific circumstance, but whenever I feel inflammation, my stomach acting up, too much nerve or muscle pain, bur especially any sort of infection I go higher, otherwise I stay in my normal dose (10 mg but I also take tryptophan).
Some people do the height/weight ratio but I don't, I take what I feel it is needed, rarely 60 mgs.
Metformin has no toxicity BUT it will deplete/impair the absorption of some B vitamins long term which can be easily remediated by just supplementing the B vitamins, but for most Americans Berberine is a better and easier (and cheaper) choice.
Whenever you read me talking about metformin you can instantly substitute for berberine, it is almost a perfect analogue to metformin.
You can take it interchangeably, but I would rather you just take Berberine unless there is something unique of Metformin that you want (there are very few things one does that the other don't).
I have a lot written about it I will link it all together tomorrow most likely. Berberine is a better choice and easier to get if you are American or European.
It is more about the absorption rate than efficacy I have huge disagreements with the bioavailability "science" from personal experience and hundreds of people I came to help as years went by.
Some will act much faster and better, and would be preferably taken on a empty stomach, such as tryptophan or melatonin.
NAC on a empty stomach can be pretty hard because the A, Acetyl is a known gastric acid agonist, it will make you produce more acid and some people won't do well on that (I am one of these). Hope this helps and clarifies things.
Reckon it could be a dodgy brand of NAC? Or has it gone bad? But I think if it goes 'bad' it becomes Di-NAC which is better. Or maybe its reacting to something else you take? I know I feel nauseous with 1.5mg of melatonin.
Thank you! Thank you! Thank you! I love when you write the way you do! I remember you said that sometimes you take up to 30mg Melatonin. How do you decide when you will take 30mg or less.? Does it go by height/weight ratio.? Also, i read that metaformin has some toxicity and that berberine might be better although they work slightly differently..what do you think? Can we use berberine and/or metaformin interchangeably or just metformin?
I have a very specific circumstance, but whenever I feel inflammation, my stomach acting up, too much nerve or muscle pain, bur especially any sort of infection I go higher, otherwise I stay in my normal dose (10 mg but I also take tryptophan).
Some people do the height/weight ratio but I don't, I take what I feel it is needed, rarely 60 mgs.
Metformin has no toxicity BUT it will deplete/impair the absorption of some B vitamins long term which can be easily remediated by just supplementing the B vitamins, but for most Americans Berberine is a better and easier (and cheaper) choice.
Whenever you read me talking about metformin you can instantly substitute for berberine, it is almost a perfect analogue to metformin.
You can take it interchangeably, but I would rather you just take Berberine unless there is something unique of Metformin that you want (there are very few things one does that the other don't).
Thank you. All noted and learned by heart.
Good call John Paul! (that has a nice ring to it)
https://pubmed.ncbi.nlm.nih.gov/33670363/
Viruses
. 2021 Feb 11;13(2):282. doi: 10.3390/v13020282.
Berberine and Obatoclax Inhibit SARS-Cov-2 Replication in Primary Human Nasal Epithelial Cells In Vitro
Thank you from someone with vaccine-induced long COVID. I’m going to inquire about metformin
I have a lot written about it I will link it all together tomorrow most likely. Berberine is a better choice and easier to get if you are American or European.
Berberine also very easy to acquire in Aus. Metformin requires Drs prescription.
I used to be able to take NAC with no problem, but now it gives me an unbelievable stomach ache. Why would that start to happen?
Are you taking it on a empty stomach?
Yes, thought it was supposed to be (as amino acids are generally recommended)
It is more about the absorption rate than efficacy I have huge disagreements with the bioavailability "science" from personal experience and hundreds of people I came to help as years went by.
Some will act much faster and better, and would be preferably taken on a empty stomach, such as tryptophan or melatonin.
NAC on a empty stomach can be pretty hard because the A, Acetyl is a known gastric acid agonist, it will make you produce more acid and some people won't do well on that (I am one of these). Hope this helps and clarifies things.
Got it, thanks!
I thought it was best to take NAC on an empty stomach. Are you saying it should be taken with food?
For some people absolutely, and this "taking X on a empty stomach" is kinda bogus for a LOT of things. Just makes absorption faster most of the times.
Reckon it could be a dodgy brand of NAC? Or has it gone bad? But I think if it goes 'bad' it becomes Di-NAC which is better. Or maybe its reacting to something else you take? I know I feel nauseous with 1.5mg of melatonin.
I thought you liked glycine? No?
Glycine+NAC for synergy and potentializing effects of each other, yes 😁