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Dee Lau's avatar

Fascinating take on the gut microbiome and SARS-COV-2. I've been taking ProBio7 supplements daily (it has the usual Lacto and Bif bugs in there). I remembered reading Sabine Hazan's Progenobiome research on X, saying the Bif bugs are absent in the mRNA jabbed primarily. I guess the same would apply to those who caught it naturally.

Is it worth taking NMN supplements daily? I've just finished my turmeric+ boswelia and looking for the next super-effective boost for my health stack.

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Moriarty's avatar

Whenever most "influencers" find an avenue to virality and stardom, they will attach to it, which is the case with Hazan and many others. Biffido also suffers heavily from the natural infection, but tends to recover after many months, in severe cases, it stays dysfunctional for a long time. Although the mRNA take such massive damage to their microbiome that I understand the focus.

Wonder if Akkermansia suffers the same from the MRNA.

Well, depends on the budget, it can be worth if in your region is not super-expensive, for the most part I recommend NMN "break glass" or when sick, Nicotinamide or Niacin Flush for continued supplementation.

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Perplexed Rationalist's avatar

One thing which I think gets missed with Vitamin D though, and this is different from earlier in the pandemic because it is purely because of the stealthy way Omicron suppresses the initial immune response: I would suggest pausing VD supplementing for the first 3-4 days if you are infected with covid (as well as antioxidants) because it’s immune modulating effects could be counterproductive when you actually need some degree of inflammation and oxidative stress. On day 4-5 you hit it hard again and of course I believe you should be supplementing it everyday usually. It’s just taking a pause while you try to kickstart an immune response (ginseng, interferon spray, astralagus, artemisinin for example)

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OneDayAtATime's avatar

Moriarty, thanks for a great article. I started taking NAD + and it's really helping with the fatigue from long covid. Question for you. An MD told me that in her experience the effects of NAD + supplementation are temporary. What is your experience with this? Thanks!

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Moriarty's avatar

I am happy NAD+ worked for you. And yes, the MD who told you that is correct, it is not just her experience. Some people may find lasting relief with NAD+ but many Long Covid will find relief that may decline because whatever is "draining" your NAD+ pools remains to be addressed.

Supplementing with Nicotinamide while in the stage where you feel improve fatigue can help the effect last, assuring your body has a steady flux of NAD sources other than breaking down tryptophan.

Adding some sort of antioxidant would help too, many Long Covid experience improvement with NAC+Glycine (I have an entire article on NAC+Glycine alone). Creatine + 3 grams of sugar will also help keeping the fatigue away (also have articles on that).

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OneDayAtATime's avatar

On a slightly related note have you explored the impact of mycotoxin antibodies on long covid? There seems to be a bit of a buzz about mycotoxin antibody blood tests but very little about how to address positive results except for certain probiotics.

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Moriarty's avatar

There are many subsets of Long COVID patients and I have long argued that besides latent viruses, fungal/yeast infections especially the subclinical ones, the ones that have no observable symptoms play a part on it.

COVID can create a "amnesic" state in the immune memory against fungi. I am not surprised they are finding mycotoxins at all.

Similar approach to dealing with other toxins + attacking the fungi directly which vary by which one sometimes.

Boosting immune function and activated charcoal (to bind, neutralize and remove part of the toxins so the body has spare we everything) are a must in these cases.

Some people experience great improvement in symptoms by using either Metformin or Berberine, worth a try if you haven't (either is good. berberine is natural though)

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OneDayAtATime's avatar

Thanks for the detailed response. I appreciate "amnesic" state. I now rarely get cold or flu symptoms any more and I am far less prone to inflammation but my sense is that there are still tissue bound toxic elements that I need to get rid of. I love oregon grape root tincture which is a great natural source of berberine. I am also pulsing chlorine dioxide/dmso for the fungal stuff resulting in significant herxing. And yes my exercise tolerance has risen dramatically through all of this. Persistence feels key.

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Moriarty's avatar

Not getting a cold or the symptoms is a great sign of a better overall immune system, and being less susceptible to inflammation is also a great sign, my guess is that you have made good progress over time. It has been my opinion that we have been tackling some toxic remnants of the things we got infected with in the last 3 years.

Persistence is key, I have written about my experience with the goal of perhaps helping some people a couple ofyears ago, and I am a huge proponent of mind over body. To me, the mind is 50% of the effort, supplements and all else the other 50%.

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OneDayAtATime's avatar

Thanks for your encouragement. Re: toxic remnants, that's exactly how it feels, plus I have remnants from earlier parts of my life like having a parent who was a heavy smoker. It all builds up until we address it.

Yes! Mind and attitude matter a lot. It's amazing to me how many people just give up. I like the classic image of the frog strangling the pelican as the pelican is trying to swallow it. 😀

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OneDayAtATime's avatar

Thanks for the detailed response. I take NAC daily as well and I have been thinking about trying Creatine. I will review those articles. Thanks for all you do.

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toolate's avatar

Thanks!

Tried L Reuteri but came back to B. Infantis

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GardenJilly's avatar

First hand experience with the gut and Cov Alpha infection. My son got eczema after his infection. We did a gut test last year and he had some nasty stuff in there H pylori, CDiff, Psudonmias Poor kid.

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The TX Blue Lady's avatar

The main question is where to get the correct Probiotic? Dr Hazan won’t say.

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Moriarty's avatar

Specific strains may be patented sometimes, but they are not exclusive, meaning the patent holder gets a cut, that is all.

Find a reputable source with good reviews, and buy the strains you think suit your needs. There is really no "secret" to it, Hazan can't say because she is a doctor and that would constitute medical advice (guessing here)

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Alamo Dude's avatar

Lobelia and Kiefer. Studies in 2020-21 showed Kiefer mitigated Cov19 Cytokine Storming.

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Moriarty's avatar

I have covered the "NAC is harmful" before

Unless you have that gene mutation that makes you accumulate homocysteine, NAC is very safe.

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