14 Comments
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Sally Gould's avatar

This post should garner much praise for you. Your research efforts into TH17 are all coming together in one jigsaw puzzle. ... Thank you!

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Moriarty's avatar

Thank you for your kind words Sally =). I will fit even more pieces into this massive jigsaw puzzle this week.

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William Hunter Duncan's avatar

DeSantis is not going to want to hear that about monoclonals.

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CaliforniaLost's avatar

Hahaha,, you have got to be kidding me, Peter Fing Hotez? That duplicitous hobbit was on the 17 case back in 2020? That makes his actions even more bizarre. Unless... huh, well, that is an interesting twist in the corona plot.

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Moriarty's avatar

I was also surprised when this was shown to me by the person who I collaborated on the PAID theory.

He was fully aware of the immunological responses of SARS, and consequentially SARS 2, and knew there was a massive chance this would occur. I guess it was a preemptive "get out of jail card" if SHTF "BRO I WARNED YOU".

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Cube Cubis's avatar

If Th17 gives a massive inflammatory response then it's very very bad. Hence so many people with bad allergies and weird or flaring up auto immune issues... maybe in a fit dude who ketos a lot it doenst matter but for the average slob its a killer??

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Moriarty's avatar

Yes, a continuous stimulation of Th17 will inevitably shift the immune system into a dominant state (meaning it doesn't go back, you stay at that immune response for months/years) and yes it is one of the reasons for all the weird shit.

If the average slob has a poor diet, and eats lots of carbs, yes, it is a medium/long term killer.

Th17 when it feeds disease is long-term misery.

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Cube Cubis's avatar

i think you mean dormant state?

god every day i wake up and thank the flying spaghetti monster i am not jabbed.

I will start writing again. min once a week. would appreciate if you subbed me :) more analysis via humour than deep thought

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Moriarty's avatar

No, dominant. Your immune system lives in a equilibrium.

Th2 dominant state = allergic state, for example.

Will do.

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Elchavodel8's avatar

Hi John Paul! I have a question, hopefully you can help me. There's a lot going on at the molecular level and it becomes somewhat confusing. My understanding, in a nut shell, is that the repeated vaccination potentially exposes the person to a very high amount of spike protein, which by itself is very problematic because of it's interactions with receptors and molecular mimicry. And also, that repeated exposure to it, primarily through the vaccines, or more so than the infection, shifts the immune system to tolerate the spike by altering the types of abs produced. Did that sound correct?

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Moriarty's avatar

Hello. Let me see if I can help you. Repeat vaccination exposes people to large quantities of Spike protein, in which by itself is inflammatory, and causes shift in the immune system and metabolism, along many other changes.

Molecular mimicry soon follows as a consequential problem.

Correct, repeated exposure more to the vaccine than to the infection shifts the immune system towards a less inflammatory, and know we have parts of the reason why, because levels of ADE were occurring in Delta and in all waves of Omicron.

So yes, while I don't like the terminology "spike tolerance" it is a good description of what is going on, it is more "inflammatory hedging", attempt to avoid massive amounts of inflammation with each exposure, because a lot of the repeated vaccinated always have high viral load.

Hope it helps.

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Elchavodel8's avatar

It does. Thank you!

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Vxi7's avatar

Ahahah Hotez knows? Seriously?

Other news today:

Sun is shining so it's warm...

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Mary's avatar

Perhaps Dr Hotez has a treatment waiting in the wings for the pharma cartel that the ADE stricken will be begging for. $$$$$ Problem - reaction - solution $$$$$

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