Viral clearance in patients with COVID-19 using hydroxychloroquine

And azithromycin

While I work on another piece to be published tomorrow, also in the veneer of this one (positive news), I decided to write this short substack to “add to the pile” of evidence, so you too can tell some people “I told you so”. Also, a mild excuse to make a “hidden” substack a little bit more known.

Paxlovid use becomes dangerous, HCQ works

Ironically, I will refer to the piece above again, tomorrow.

The use of HCQ was always real, there were many mechanisms besides the one described inside the substack above, with one of the major ones in my opinion being its immunosuppressive effects on a specific class of T helper cells. Th17.

Now that the pandemic has reached its “end”, mainly most of society doesn’t care about it anymore, and on a large scale its politicization is gone, real-world evidence is finally being published without absurd backlash.

Viral clearance in patients with COVID-19: associated factors and the role of antiviral treatment

The role of hydroxychloroquine (HCQ) in lowering the viral load of patients with COVID-19 is controversial. In our Institute, we treated more than 30,000 people with COVID-19 in 2020 and 2021, using the same diagnostic tools and the same treatment dosages. In this retrospective comparative study of data collected over this period, we aimed to compare the viral clearance in the nasopharynx as determined by qPCR in patients who were treated with HCQ and those who were not. As a new feature, we adjusted the data according to the most significant confounding factors (age, initial viral load, and timescale between the onset of symptoms and treatment). Of the 1 276 patients selected from our database, 776 were treated with HCQ and 500 were not. Viral clearance in the treatment group was reached significantly earlier than in the non-treatment group, at days 5, 10 and 30.

These differences remain significant after adjustments for confounding factors. In conclusion, although age, initial viral load, and time to treatment do influence the viral load in patients with COVID-19, hydroxychloroquine associated with azithromycin still independently significantly lowered viral load more rapidly than other treatments, including azithromycin alone

There was extensive evidence since 2020 that HCQ worked at many different levels, and after a few months of clinical use, many clinicians swear by anything and everything HCQ+AZT lowered the viral loads, lowered fatality rate, and all a significant amount of the worst outcomes post-infection.

Now we have stronger evidence on the effects of using HCQ+AZT to treat the infection itself and its effects on viral load, and viral clearance, both aspects are significant on the overall course of the viral infection/disease, a simplified approach to this follows:

• The lower the viral load gets, the less chance and possibility you have to develop any of the myriads of after-effects the virus may induce, you also avoid developing acute and severe forms of the disease

• The higher and faster the viral clearance, the same applies, you effectively lower your chances of developing ANY long-term problem from the presence of the virus or viral particles

Are you curious to know if any pharmaceutical company knew the combo of HCQ+AZT was effective in the treatment “Covid pneumonia” back in 2020 ? Because one company did know, and ran clinical trials finding exactly what we just covered. This company also owns the world's foremost “expert” lab on researching the use and creating new synthetic forms of anything chloroquine.

HCQ and evils of Pfizer

Now here is something I left in comments here and there, but never outright said out loud, I also can’t back it up because this was scrubbed incredibly hard from the face of the internet, and back in the early days of the pandemic, in 2020, I didn’t have the habit of screenshotting and archiving anything of any level of interest.

Pfizer had an instruction set inside some of the vials of its mRNA very early on, and a PDF document that was scrubbed within 2 weeks from the face of the web, and the instructions were clear. In case of any form of adverse events or adverse effects, HCQ should be used to treat the symptoms and said effects.

It is my opinion that Pfizer knew from very early on, despite most of its scientists denying it to this day, that its mRNA vaccine had an overwhelming aggressive immune response that skewed very early, very heavily towards Th17.

We could have avoided a lot of deaths, many of the immune-mediated outcomes, and a substantial amount of the mRNA damage if this drug wasn’t so heavily politicized, and our supposed betters (academics, doctors, scientists) didn’t fall for the psychological operations and corruptive efforts of a small group of individuals and a few companies. One of the very few aspects of this whole mess that actually enrages me.


FYI, HCQ (and AZT) should not be used willy-nilly, but it is a powerful tool to have in your “tool box”, the famous “break glass in case of emergency”, I also have the suspicion some of the vaccinated with different types of damage would do well in a short-course of the combo, with medical supervision. Drugs are not like supplements, and HCQ while not exactly dangerous, is an immune modulator, and AZT is an antibiotic, and antibiotics should be taken only if they are really needed because you are carpet bombing your microbiome as a side-effect for a short while.

Gratitude to the subscribers who choose to support this work !