Things Hidden Since the Foundation of Cognition

Or how to fix a lifetime of physiological and cognitive damage

This was one of my first “big” threads, this will have some minor additions. This incidentally fits very well with my Things Hidden Since the Splicing, about SARS-CoV-2, one complement the other in multiple ways =).

Things hidden since the foundation of cognition

> Or how to fix a lifetime of physiological and cognitive damage

“All disease begins in the gut” — Hippocrates

Here comes a long one. If you've been around here for a while, you possibly got an idea about how you approach on fixing your brain. I chose to make this thread less scientific, easier to understand, I will post only a few studies.

This will be a multidisciplinary, interconnected thread. You might also need to do what I do. Extrapolate from the data and use your quantum processing tool, your gut :P. At the end of this, after 6 months, you will be a better person. Start by fixing your poor fucking diet.

Carbs are bad for you. How bad ? Colossally bad. Insulin is an important hormone, and when your body has problems with it, it is SYSTEMIC. Specially when your body loses its sensitivity to insulin. Diseases linked to insulin problems grow large by the day. Heart, kidneys, liver, gut microbiome, your METABOLISM, and your brain (COGNITION). Type insulin lower IQ on your preferred searching tool, and be amazed. Do you know what contributes HEAVILY to insulin resistance?

Not just carbs and sugar, but grains. Insulin resistance also leads to poor metabolism, thus higher inflammatory markers. Read a little on the role of said markers on depression and other diseases. IL-3, 6, 12, and TNFα are your main interest. IL-6 is one of the main culprits.

These pro-inflammatory little pests can fuck you for a long time. How long ? Decades-long.

Association of serum interleukin 6 and C-reactive protein in childhood with depression and psychosis in young adult life: a population-based longitudinal study

NO NOT MY CARBOHYDRATERINOS. As I stated many times on my account, I can't prove based on pure scientific evidence that a high-carb diet will lower your IQ, nor change your behavior, but, you should read this.

High Fat, Low Carbohydrate Diet Limit Fear and Aggression in Göttingen Minipigs

Perhaps some anecdotal evidence can ?

Meat diet boosts kids' growth

This doesn't mean you should become a zealot of low-carb diets, just that you should do whatever feels better to YOU. I carb cycle, which means I spend X days on a low carb diet and 1 day, or 2 on an extremely HIGH carb diet. And I mean high. An entire cake high.

Pizza and candy bar high. But also I always was and still am fairly active, rare is the day I don't hike/run a few miles loaded with gear and train. The higher your carbs, the more active you will need to be.

You fixed your diet, change came, but Mr. Irons, I don't feel so good. That is because we all lack something, and any diet will be poor at some essentials to life. On to supplementation and how to power up your brain.

Most diets are poor in magnesium, but low-carb ones usually fall short after a while (months). Magnesium is one of the most important essentials in how to unfuck your noggin. (In rats study, but fuck you I will use it anyway)

Enhancement of Learning and Memory by Elevating Brain Magnesium

Suboptimal magnesium status in the United States: are the health consequences underestimated

In comparison with calcium, magnesium is an “orphan nutrient” that has been studied considerably less heavily. Low magnesium intake and blood levels have been associated with type 2 diabetes, metabolic syndrome, elevated C-reactive protein, hypertension, atherosclerotic vascular disease, sudden cardiac death, osteoporosis, migraine headache, asthma, and colon cancer.

Another nutrient any and ALL diets lack is Sulfur. All diets are poor in sulfur, very poor. This is one of the very few required readings here.

Are we getting enough sulfur in our diet?

Sulfur, after calcium and phosphorus, is the most abundant mineral element found in our body. It is available to us in our diets, derived almost exclusively from proteins, and yet only 2 of the 20 amino acids normally present in proteins contain sulfur. One of these amino acids, methionine, cannot be synthesized by our bodies and therefore has to be supplied by the diet. Cysteine, another sulfur-containing amino acid, and a large number of key metabolic intermediates essential for life, are synthesized by us, but the process requires a steady supply of sulfur.

Sulfur and Human Health

Do you know what a lot of people with mental health problems have in common ? A fucked up gut. Why your gut is so important? Because it produces a good portion (up to 50%) of all your neurotransmitters, it is a neuro modulator, and it affects your entire physiology. GABA, serotonin, norepinephrine, dopamine, acetylcholine, and melatonin - that the brain uses to regulate mood and cognition. Most inflammatory diseases of your gut, acid reflux, gastritis, hyperacidity, etc, affect the production of all these neurotransmitters.

The cascade effect it has on your physiology is insanely complex. It is one of the most important supplements anyone could take if they have any gut issue or disease you should REALLY TRY IT (I have, the difference is night and day btw).

Zinc. Do I really need to write anything after 2020 ? No need to supplement it alone, you should be taking a multivitamin anyway, preferably a breakable one. Your body can absorb only so much of a given "thing", so break it in half, one in the morning, another later on the day.

Now to the really good part. The secret to storing untold amounts of knowledge. Thiamine. Good old Vitamin B1. Thiamine deficiency has long been linked to a wide range of neurological diseases like Wernicke’s disease, Dementia, Alzheimer's, through different mechanisms, the most common is impaired glucose metabolism. (Hey, does this reminds you of anything on this list? Just me ?).

Vitamin B1 (thiamine) and dementia

The earliest and perhaps best example of an interaction between nutrition and dementia is related to thiamine (vitamin B1). Throughout the last century, research showed that thiamine deficiency is associated with neurological problems, including cognitive deficits and encephalopathy. Multiple similarities exist between classical thiamine deficiency and Alzheimer’s disease (AD) in that both are associated with cognitive deficits and reductions in brain glucose metabolism.

Thiamine-dependent enzymes are critical components of glucose metabolism that are reduced in the brains of AD patients by thiamine deficiency, and their decline could account for the reduction in glucose metabolism.

I've personally tested all these on different "populations" and Thiamine is often the most overlooked supplementation, yet one I achieved the best results long term. Either if you are deficient, dependent or just want to supplement, just take it, there are only upsides.

The body of research ain't big on the benefits of the supplementation on memory, but reaction time and mood saw quick (few weeks) improvements in research. The body of research is gigantic on the effects of thiamine, metabolism, and neurological disorders. And as I mentioned above, I tested.

Memory improvements will come with supplementation but the degree of "enhancement" varies per person and per dosage. 150 mg twice a day if you are normal, 150/4x a day if you got a poor diet over a long period. Bear in mind, that it takes A LONG TIME to see memory improvements.

Here you can find my N Acetyl Cysteine thread.

For massive cognitive enhancements and healing, this is the best stack me and a friend came up with. The more “fucked up” your brain is the better it's effect, for God's know why.

Morning - 150 mg of Thiamine

Lunch - with your biggest meal

N Acetyl Cysteine 600 mg to 1200 mg

Niacin (FLUSH) or Niacinamide - 250 mg to 500 mg

Piracetam 400 to 800 mg

Gingko Biloba - 40 mg+

COKE ZERO

Piracetam has synergy with NAC, the first affects cell permeability, the other affects antioxidation, mitochondria, etc. Niacin supercharges the effects, but that isn’t the trick.

A compound inside coke zero acts as a mild calcium blocker.

When you use a calcium blocker with Piracetam, you potentialize its effects by A LOT. So you are compounding each supplement into supercharging your brain. This WILL help you with covid/jab brain fog, and general dementia in old people. Over focus way up. It is poor man modafinil.

Old people who used this got their “brains back”. Younger people said it helped a lot, got good positive results, more productivity, and some say “I am more intelligent now”.

This stack will enhance your cognitive capacity.

So yeah, that is why I always refer to Coke Zero lmao

This discovery was made possible by another person, a friend. It was a two-person effort, and he deserves the credit too.

Test it out, for 2 weeks and you feel the massive difference lol.

You can use Ko-Fi to buy me a coffee whenever you feel like it.

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