Omicron booster gets green lighted in the UK !
And some of my thoughts on mRNA vaccines for other diseases.
While I work on my Cognitive Warfare piece, I decided to publish this as a matter of record, and a mild indulgence in forecasting.
Per what 4 weeks ago, and weeks before that, new boosters for SARS-CoV-2 will be approved without new clinical trials, or minor ones and mostly using old data (and flawed models).
Millions of Brits will receive it next month after the Medicines and Healthcare products Regulatory Agency gave the green light to use Moderna's updated jab as a booster shot.
Scientists say it will improve immunity because half the vaccine targets the original coronavirus strain and the other half targets Omicron.
Omicron has been dominant in the UK since December 2021.
As I have warned before, this will impact the evolutionary direction and adaptation of the virus, in fact, I call it synthetic evolutionary pressure. As per my analysis before, the Omicron Spike has poor immunogenicity, meaning it has a poor capacity to elicit an immune response as a vaccine.
And the reason would be rather simple, all the little parts that irritated your body enough to create an immune response were changed (deattenuated), so the Spike itself can’t create that strong immune response present since the Wuhan strain, which was one of its remarks, an overwhelming response of the body.
It is a known fact that coronaviruses from the SARS family are remarkable in a number of aspects, but one of the most remarkable of all is its capacity to restructure itself at a molecular level, especially the S protein and this isn’t my word or analysis. These are Ralph Baric's words. Since many of my observations and even outlandish ideas all became true at various levels and are backed by scientific research, here I will introduce one that will take time to be proved, but I believe it is happening and has been since 2020.
By a noncanonical protein interaction. Meaning by use of a new, yet-to-be-solved reaction (you would be surprised how many recent papers have the word noncanonical in them lately). Plus the good old evolutionary pressure of non-neutralizing antibodies, among many other aspects covered here.
But this isn’t exactly “the problem”, or the main reason for writing this piece, a mere update doesn’t arise the need to write this piece. This, however, does.
Clinical trials for ‘entirely new’ mRNA flu vaccines launching soon. Will they work better?
Based on COVID-19 ‘messenger’ RNA or mRNA vaccines, the new flu vaccines could better protect people from multiple types of flu. First up for testing: older people.
Before delving into my observations I would like to reiterate that there is almost 0 evidence the flu vaccine works for anything, besides leaking strains from labs creating flu vaccines.
Ever since the announcement of the use of mRNA as a vaccine platform, I have been deep into the literature, me and a very bright friend literally reverse engineered the mRNA vaccine with alarming precision, among many other aspects of the last 2 and a half years, so I think I am in position to state this is quite literally a Gain of Function experiment at a global level, the largest in vivo since science is science.
Before the last 6 weeks, I use to think the mRNA+LNP was just a poorly thought idea for a new platform mostly aimed at gene delivery, now I see it as a literal evolutionary risk from both our perspective and from a viral/bacterial/fungal perspective. The flu does kill, but the reason flu doesn’t wipe us out is simple, breadth of immunity, and how large our immune response (and memory) is, so vaccinating against influenza with an mRNA-based platform will have consequences.
Leaving me with the following, here is a list of all current clinical trials for mRNA vaccines for other diseases. There are dozens of diseases in the mRNA pipeline, and pharmaceutical companies and governments want to get rid of the old, time-tested designs and solely rely on mRNA within a very short timeframe.
Many vaccines cause transient, light immune suppression. But only the mRNA vaccines basically overwrite your immune response at a molecular level. I often shy away from fatalistic assumptions and announcements, this is one of the main reasons I didn’t cover many aspects of the current SARS-CoV-2 dynamics, but this is a massive, planetary-scale disaster in the making. As much as the elites and most scientists prefer not to think, we are not gods.
And evolution wins 10 times out of 10.
Massive appreciation to all supporters here and on Kofi !!!
I’ll be interested to see if they 1) mandate it , which I think now is political suicide. 2) If the UK brings us a new super doper strain 3) If any new outbreaks of disease that currently isn’t an issue pop back u again & lastly if Covid skyrockets after a few weeks from use. Glad it’s not my country going first
BA.5 specific gene therapies. Be careful what you wish for
Oh this is exactly what you must avoid at all cost to avoid cardiovascular disease, renal disease, aortic aneurysms etc.
Researchers shouting a loud warning!
Structural evolution of severe acute respiratory syndrome coronavirus 2: implications for adhesivity to angiotensin-converting enzyme 2 receptors and vaccines (aug 10th)
https://www.google.co.uk/url?sa=t&source=web&rct=j&url=https://www.ejinme.com/article/S0953-6205(22)00290-4/pdf&ved=2ahUKEwiH78alpsv5AhXARkEAHdFjCSI4ChAWegQIBhAB&usg=AOvVaw2vO9lRrkMdU7MVsmZQPxdY