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Moriarty's avatar

I need to publish one more article, which the paper itself is (to me) as significant or more significant than this one, than I will focus on the simplified stack and the missing piece of the puzzle, which I have been working on for weeks now.

I wish everyone a great week ahead.

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rjt's avatar

Your last article with the Japanese cancer mortality is interesting.

1) The last phrase "May be due to reduced screening-" is of course a lie, but necessary to get published. Cancers for which screening may be useful do not kill in a year, otherwise we would need weekly or monthly screening.

2) The estrogen receptor comment was quite evident from the earliest reports of Covid and the vaxx, in which women reported menstrual disturbances. Recall that the spike abundance after a shot is about 14 Trillion! times greater than after an infection.

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NJ Election Advisor's avatar

You’d love Japan - at the street fairs they sell giant beetles to bring home and feed and watch. It’s pretty cool.

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Moriarty's avatar

=( I am sad since I can't buy giant beetles and raise them now. And yes, I would love Japan. I learned Japanese long ago because of how much I liked the culture, etc.

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Nicole's avatar

Watashi mo!

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Bandit's avatar

Gross.

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debra lenz's avatar

Are you familiar with Michael Nehls research on the spike affecting the Hippocampus region, blocking creative thinking? This may have something to do with the puzzle. "The Indoctrinated Mind" very interesting reading. How do reverse this? I am a long time meditator and believe this offers potential for healing the Brain.

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Moriarty's avatar

Not familiar with the work.

Meditation and breathing techniques work wonders for healing all the body.

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CecilRhodes's avatar

He (Nehls) is the fellow recently interviewed by Tucker Carlson. He's an Alzheimer researcher big on low dose lithium. Lithium certainly has some interesting electrochemical properties. Worth a look IMO. A causal google shows studies on anti-inflammatory / neuro -protective properties with papers on the dementias, Huntingtons, ALS and Parkinson's. Looks like low dose lithium is a hot topic in that regard. There are also papers on lithium as a potential treatment for IBS due to regulation of the gut microbiome. For example https://pubmed.ncbi.nlm.nih.gov/34801681/#:~:text=GPR43%2Ddependent%20manner-,Lithium%20carbonate%20alleviates%20colon%20inflammation%20through%20modulating%20gut%20microbiota%20and,doi%3A%2010.1016%2Fj.

Something to consider.

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DoorlessCarp🐭's avatar

🤔

A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication (2010)

...The linkage study discovered a genome region harbored in the Latrophilin 3 gene (LPHN3). In the world-wide samples (total n=6360, with 2627 ADHD cases and 2531 controls) statistical association of LPHN3 and ADHD was confirmed. Functional studies revealed that LPHN3 variants are expressed in key brain regions related to attention and activity, affect metabolism in neural circuits implicated in ADHD, and are associated with response to stimulant medication. Linkage and replicated association of ADHD with a novel non-candidate gene (LPHN3) provide new insights into the genetics, neurobiology, and treatment of ADHD.

https://www.nature.com/articles/mp20106

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Moriarty's avatar

LPHN3 in and on itself impacts the neurons in ways that shift the cognition and behavior for a long time, but you add a few other proteins and it becomes concerning. This being among them.

You will enjoy the next one article =P.

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NatteringNaybob's avatar

Professor - cAMP "a secondary messenger of some sort in the synapses" Not so fast Joe. One might want to consult their cAMP counselor. The cAMP - PKA - CREB pathway and cAMP GPCR triggered cascade in cell messaging impacts every single thing you have mentioned today (and on many other days) including the dumbing down. In addition, it's catalytic sub-units make their way into the nucleus to influence transcription. NISM Mr Mulder?

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Moriarty's avatar

Baby steps. We will get to the "nucleus" of these questions in due time, thanks to you hehe. And indeed cAMP is a essential pathway, PKA and CREB are rather peculiar or singular in regards to oncogenesis.

cAMP itself is headache indicuing at this point lmao. Reminds me when I had trouble understanding HERVs (still do, but know I know much more).

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RANGER71's avatar

Love the beetles 🪲 amazing picture ❤️ thanks!!

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skylover's avatar

something in disguise enters via nose, mouth or eyes, whatever way available,then instead of going down its choosing to go up, and settle down there (maybe the CNS) permanently, without much symptoms too...if nothing is done to get it out assuming its something mild then after a few months or more its going to cause issues to ear (middle ear to be specific) eyes,headaches and improper breathing....i think MB with NAC and C, Niacin the great with your brain stack 2.0 or 1 or some additions here and there, Melatonin , creatine ,serrapeptase and nattokinase, activated charcoal, d3,k2,mg and Boron too and of coiurse IF regular basis does solve the issues as of now...but definitely since now CNS is the main target and probably we cant live without some supplementation for rest of our life (hate it but probably its a must) ....kindly note : not all supplements daily but something or other in combination kind of daily keeps one in good shape!

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Moriarty's avatar

Pretty much where I stand on, with almost the same recommendations, but a minority of people may need daily supplementation (me as an example) but we will be outliers.

It is very hard for most people to accept this, so I don't even try, I write the information, and people use as they see fit.

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SteveBC's avatar

Wow, Moriarty, that neural stuff is *nasty*. Your comment about being dumber by being slower reminded me of when I got severely depressed (due to massive inflammation due to infected wisdom tooth sockets). When I was young, I often had the experience of having someone say something and then my mind would become an image of a widening network of connections as the thing said ramified through my mental space. When I got depressed, that ramifying process became very crippled and slow. As I worked my way out of the inflammation over the next several years and began treating myself, that ramifying process came back. Now that I'm 73, that happens less than it did. I'm wondering if the depression/inflammation process and how it gets treated might give you a leg up on finding a solution. I must say that I have had 2-3 quick bouts of C19 but so far do not see any significant long-term issues. My thought is that the C60 in coconut oil product I use may be addressing that central inflammatory issue. It's an unusual type of anti-oxidant/anti-inflammatory that I have benefitted from quite a bit over the past several years, and no other substance has done what this one does.

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Moriarty's avatar

My situation is fairly unique, and I "gave" msyelf 3 infections with the strongest possible strains early in the pandemic (so we could understand it better), and those infections served as the solid groundwork for all our future research, this alone had a cost, especially to my immune system.

Me feeling dumber has to do with both all the infections I had, stress, and literally so much information and things I have been tackling, plus the fast pace learning. I just need to organize myself and start dumping information on paper and digitally too lol (yes I keep most in my head).

Depression and inflamation play important roles in their own negative feedback loops that feed each otehr "pathways", both processes will affect the brain metabolic rate, nutrient storage and usage, how the brain cleans (glymphatic system) itself, therefore the "junk" accumulates which will impact your mental space.

Most people will be able to recover, I am just an outlier, with severe brain damage so I use myself as a way to find ways to treat others that doctors can't or miss.

While it has been just a few days, I am surprised on how Olive Leaf Extract is already acting, so we may have other alternative (my body doesn't like to digest oils and fats that much, knife wound).

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SteveBC's avatar

Now that is dedication. I wanted to help people during the pandemic, but deliberately infecting myself with three of the most damaging variants was definitely not on my bingo card! Given all that you do and your ability to make connections even with that damage and more brain damage to boot, I find it rather inspiring to think what your potential for connection-making and idea-net visualization would have been without that stuff screwing you up. Many years ago I read David Allen's book "Getting Things Done" and was seriously impressed by the idea he espoused which was never to hold more than one idea in your head at a time. I now use OmniFocus as a task management system (which is what it is designed for) and also as a Personal Information Manager to organize information over time so I don't lose important data. It works pretty well, but it has also taken a lot of time to get it right for my needs. I definitely applaud your idea to reduce mental stress.

OLE is quite helpful. When my mother's doctor found my mom had high blood pressure, she wanted to put my mom on standard BP drugs. I said, "Give me a few days to think it over" and came up with Garlic and OLE to try. It turns out that they worked rather well, at least as well as any BP drug would have. And before that, my mother was freaking out when she moved to her residential facility, and she started to "wander." One of the people at the facility said that once people start to wander, they don't stop. I thought about it a bit and considered that wandering might occur if the person were feeling stressed and anxious, so I gave my mother "Adrenal Health" caps by Gaia Herbs to support her adrenals. Settled her right down. Herbs can be amazing.

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Moriarty's avatar

I am not trying to sound arrogant, or throw any form of negative retort towards you but my brain is now better than between 2015-2019 (I started improving during 2020, you could add 2020 and 2021). My brain now reminds me of my younger self during my math days, so I think all the supplementation aimed at cognition helped neuroplasticity, plus I have my own opinions on these subjects that goes against the orthodoxy.

I firmly believe you can increase your IQ by 15 points in a short period, with ease =P. Among other "things".

Me and a selected few had to do it, so we had some data to work with/from, they ran tests too, all sorts, among other things. Let's just say the groundwork was done on sweat and blood literally =P.

It is not just mental stress, it is more like mental...load ? As if we had a cap of instantenous information we can access at very low latency and retrieve it, so writing it down "unloads" some of that. I should go back into my younger mindset and build up the mental palace habit again, believe it or not, it actually works =P.

Interesting aspect on the adrenal health, I would have never thought about it, hum. I know it haven't been many days of me taking OLE, but I am hyper observant of myself and any changes and it already positively impacted my symptoms.

Thank you for your always thoughtful replies Steve. =)

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SteveBC's avatar

You're more than welcome. I'm enjoying reading your work and conversing with you in the comments. I'm delighted to hear you are better than your younger days and that I was wrong to interpret your comments above to think you were worse. I'd love to raise my IQ 15 points, but I am not - quite - as experimental as you. I draw the line before all versions of Coca-Cola, dude. :-D :-D :-D

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Moriarty's avatar

One of my biggest scientific inspirations is Dr. Walter Bishop, a character from the sci-fi series Fringe. You can tell much about how I think scientifically by watching the series.

It is there that I learned T.S. Elliot greatest quote. "A man only knows how far he can go when he goes too far." =P

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ME's avatar

I LOVED Fringe too!! Walter is a phenomenal character (great actor - LOTR etc)...very cool/interesting you vibe with him!

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SteveBC's avatar

I *loved* that show! Great stuff, and Walter Bishop was one reason for my fascination with Fringe. I'm not familiar with that TS Eliot quote, but William Blake had something very similar: "The road of excess leads to the Palace of Wisdom."

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sadie's avatar

Hmmm... so would this estrogen issue mean that a post menopausal woman with very low estrogen be more susceptible to developing breast cancer - or others - as low estrogen could leave plenty of room for the spike protein to bind instead? As opposed to a young woman with plenty of estrogen?

This is getting worse and worse.

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Moriarty's avatar

It depends on the cancer, it can activate the receptors even if you have low estrogen. It cut both ways, it can minimize some cancers, or incentivize others, but to me, so far, it is multifaceted.

It won't work by itself in the case of natural infection, and limiting the viral infection effects, inflammation, etc is more than enough to mitigate the oncogenesis.

At the very least, VItamin D, magnesium, the basica and usual I recommend with occasional antixodants. As long as you don't go down the infection spiral you are good. The spiral being Covid > weeks pass > bacterial or fungal infection > weeks pass > some weird gut or respiratory infection > weeks pass Covid again > repeat stage 2.

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sadie's avatar

Yikes... that last sentence describes my son. Altho since we don't test there's no way of knowing if he's getting covid or just regular colds. I'll have to look through your writings and find a few to give him to research more... and the ones with your suggested protocol. It's been almost a yr and I'm afraid he's going to get stuck at a low level of health permanently.

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Moriarty's avatar

Well, if it helps, it describes a ton of children, vaccinated or not if it makes any difference to you.

It may be Covid starting the cascade, or may be other infections sensitizing the body towards a Covid infection midway that starts the cascade.

Adjust the dosage towards his age, but many of the same supplements I suggest to adults works the same, start with the basics such as Vitamin D (remember to ajust to his age), a common multivitamin of a reputable brand, some antioxidant of your preference.

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sadie's avatar

PS - son did find olive leaf tea - picked from our tree - to really help with fatigue and brain fog but only for awhile... seemed like the body adjusted to it... maybe there is something to pulsing supplements?

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Moriarty's avatar

The extract is much more potent, so maybe buying (or making it) would be a better option, but yes, if it is only temporary it needs higher dosage or long term usage. That is why I advise a barrage of "stuff" so you just tackle everything and the body can handle the rest after.

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sadie's avatar

Thanks! He's 32 and good sized so I don't think I'll need to adjust ;) ... my unv-d dentist just called and she's sick for the 3rd time since January. If everyone's immunity is being overtaxed, isn't that going to set up all of us for more cancer, diabetes and other ageing issues? Maybe funeral stocks would be a good investment.........

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Moriarty's avatar

I often just assume everyone has young children lol. He can take the stack I suggest for most people. The dentist scenarion has become common place in the last 9 months.

Yes, if people don't take care of their immune system, we will have a deluge of those issues...

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sadie's avatar

I just searched your site for chlorine dioxide and didn't find your thoughts on it... just curious what you think since you are in the south where it seems to be popular. Good for what ails you - spike, cancer, joints - or just enhanced water?

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NotJason's avatar

Can you kindly share the paper? I want to look for the Control Group. If there is no uninjected Control Group, I immediately class all information under Injection Injury. Everyone forgets too quickly that Omicron was sequenced to being present in 2020 as well. And there is growing consensus that it is not lineage from Wuhan 1. Wuhan 1 was here since EARLY 2019 (if not long long before). And none of these issues occurred until the injections were rolled out. If these were from Wuhan 1 (subsequent Delta etc as we are led to believe) we would have been seeing this on ground level across the Glove for all of 2019 IMHO. What do you think?

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Moriarty's avatar

I am very inclined to completely ignore you by "None of these issues occured until the vaccination" which any real world, published, clinical and large scale data mining would prove you wrong.

Quite literally one could argue the opposite of what I am arguing, that all this is mostly the original strain, incidentally they would be correct, the first strain out of China was the most aggressive. Most people with damage to this day were infected with the original one. It is shifting now.

The paper was mostly done on organoids, which I explain what they here, and elsewhere. But to answer your question, for the sample from people with Covid-19 in their brains.

And the author's splicity tried to test for Spike Protein only and saw little reaction (which is something I pointed out). It is the virus, the virus has been and is now more neurotropic than before.

Patients with COVID-19

All patients (six) had a positive nasal swab for SARS-CoV-2 before

death, and were hospitalized in the intensive care unit with a severe

COVID-19 diagnosis, between May 2020 and May 2021, a period during

which the main circulating strain in France was the SARS-CoV-2 alpha

variant. Post-mortem delay before samples were taken was less than

24 h. Four male and two female patients were sampled, with a median

age of 64.5 years (44 to 79 years). Delay between COVID-19 diagnosis

and death was 11 to 32 days. Blood (sub-clavicular or femoral veins),

and cerebrospinal fluid (lumbar puncture) was taken when possible.

Samples of temporal regions of the brain lobes were immediately

frozen at −80 °C, and then the brain was fixed with 4% formaldehyde.

Frontal and parietal regions were sampled and embedded in paraffin. RNA samples were extracted using the KingFisher Flex systems

(ThermoFisher) according to manufacturer’s instructions. RT-qPCR

was performed on 5 µl of RNA using the Quantabio ToughMix reagents

(Quantabio). The IP2/IP4 probe sets38 were used to detect SARS-CoV-2

RNA onsite (hospital of Reims, France). De novo RNA extraction and

RT-qPCR analysis were performed later in the lab on other sections of

the temporal lobe of the six patients using primer N1. Glyceraldehyde

3-phosphate dehydrogenase (GAPDH) mRNA was also quantified. Cycle

threshold value (Ct) above 45 was considered negative. The Plateforme

des Centres de Ressources Biologiques of the Academic Hospital of

Reims stored and provided the sam

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NotJason's avatar

Thank you for not ignoring me. I appreciate your response, and am glad I have your attention.

There are so many anomalies and inconsistencies in the narrative, that I cannot help but to question all of it. I have a lot of questions..... can you help?

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Moriarty's avatar

That is why I stay away from "the narrative" because it is literally a "narrative", both sides are engaing in, what I can describe in plain words, bullshit.

You are coming from a heavily biased perspective, common on "our side" of the conversation, that any, and all damage was only done by vaccination. Granted, the vaccines have an atrocious safety profile, but that is long gone now, the virus mutated enough it infected everyone equally, the only variable is how much damage one was exposed beforehand (vaccinated = a lot more damage, unvaccinated = severely less, or borderline none).

In simple words as I describe since late 2021 "the vaccinated are merely ahead of the curve".

The genetic data is kinda bad to use (sequences, etc) because China literally produced a dozen or more fake sequences, every single time a inconvenient truth surfaces, that magic happens, and some sequences were uploaded before hand as obfuscation. I also have personal suspicion that the DoD and DARPA engaged in the same midway through the pandemic but with much more finesse and stealthness than their Chinese counterparts.

You are entirely free to believe it is just and solely the mRNA vaccines that induce damage, I get it, I spent almost 3 years reverse engineering this garbage product to attempt to help people that would be damaged by it, but minimizing the millions of people harmed by Wuhan, Alpha and especially Delta usually sets me off, as you can tell by my tone in the first reply.

Yes you can ask anything, but hopefully this wall of text clarifies some of my positions.

Also as a preemptive comment, I firmly believe Omicron was entirely designed as a stealth second hit. First hit damages the heck of the immune system of some, with the added vaccines for people willing or forced to take it. Omicron, second salvo that takes year to observe damage.

Third salvo is for everyone's guess.

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NatteringNaybob's avatar

Professor - "Omicron was entirely designed as a stealth second hit" Your on a roll, and not a Kaiser. One perspective vet the Omicron mutations & alleles vs Alpha, Delta & Wuhan. Brings to mind this "conundrum" and warning Mr Mulder https://youtu.be/w0MN-0i4yW4?t=54

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Cryesncoding's avatar

So can your brain stack “heal” the neurological damage?

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Moriarty's avatar

Limit the damage, and "heal" yes. The best approach is a optimal immune system, good vitamin D levels, etc.

So you just get infected once which the vast majority do, but there is a lot of people that are getting back to back infections.

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Apr 10, 2024
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Moriarty's avatar

In a sense.

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