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Martha's avatar

Thank you for the update and links. Based on early media reports, I was under the impression that the current Monkeypox was just about the same as those from Israel, United Kingdom and Singapore from 2018/2019. The "differences" seem to be quite significant.

https://virological.org/t/multi-country-outbreak-of-monkeypox-virus-genetic-divergence-and-first-signs-of-microevolution/806

https://virological.org/t/discussion-of-on-going-mpxv-genome-sequencing/802/2

FTA: "A while back we estimated the rate of evolution of variola virus (VARV; the smallpox virus) to be about 1x10-5 substitutions per site per year (Firth et al, 2010) which would translate into about 1-2 nucleotide changes per year. This is at the high-end of estimates (see the paper for others). However Monkeypox may not have exactly the same rate of evolution."

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Kirsten's avatar

Thanks so much for the update. 👍🏼🙏🌷

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