29 Comments
User's avatar
Victoria's avatar

I so appreciate the practical and informative posts. The 17-hour Islamic fast has one key difference to non-Islamic fasting: it is a DRY fast.

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Moriarty's avatar

I believe normal fasting will have a similar effect. In my opinion, the secret is not actually the fasting, but being in a glucose-deprived state, since a ketogenic diet does the same with this particular microbe.

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ASensibleMan's avatar

Any thoughts on Akkermansia supplementation directly, such as this product? It's fairly pricey.

https://pendulumlife.com/products/pendulum-akkermansia?dsc_appld=true

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Moriarty's avatar

As good an option as any of the others in this list, if you feel confortable perhaps try for a few weeks, probiotics take sometime to work like supplements, so if you try stick to it.

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Dr Linda's avatar

I saw that as well. My hope is once the population is established and thriving, I won’t need supplements; at least daily.

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bio terry's avatar

What ii also experienced when consuming too much lacto products (i used to do the raw milk kefor as well) was that i get pains allnover, like rheumatic pains and even inside the bones, which apparently can happen when you fall in the non-secretor status part of society... and i do love sauerkraut, cortido etc. Some people say one has to consume it in limited quantities, but then you are stuck with this pot full of lacto veg. So, many things seem to be good, but not everyone can consume it the usual way. I am.non secretor O bloodtype, i even tried to do goat milk, no difference. The histamine build up, think the cadaverous enzyme does it. Eating a lot of salami and fermented cheeses does the same. They all have the cadaverous enzyme in, otherwise the process wouldn't have worked. They do say 20% of people can't consume these products and if it is true, 20% of people have non-secretor bloodgroup status.

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Victoria's avatar

When you highlight in yellow I can see the highlighted text. Any other color, and I cannot read the text on my phone screen. I try so hard!

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Moriarty's avatar

That is why I leave the sources from every single paper, if for some particular reason someone can't read, they can (and should in fact) read the sources. At least that is my hope, that a portion of the readers go for the sources and learn !

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Victoria's avatar

Very true that you provide a link to every paper. I just assumed you would want all the text you highlight to jump out at your reader like the yellow does. I can always follow the links if the parts I cannot decipher would add clarification to your excellent summary. Thank you for all your hard work.

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Moriarty's avatar

The more "vibrant" the color the more important the highlight is, well this is my intention behind it at least 😆 don't know if anyone picked up on that. That is the reason I change the colors of highlights. Sadly there is no color indication tool in substance yet. I will find a work around it to be easier for most people to follow. Have a good Sunday!!!!

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Victoria's avatar

I had wondered why sometimes you choose one color over the other. I have to admit to a foolish feeling of virtue for simply wading through the excerpts you provide. I cannot imagine reading and making sense of the links. And, of course, that kind of laziness is why we live in a world overrun with and run by corrupt and stupid "experts." Thank you again.

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Cryesncoding's avatar

Didn’t your post recently say they’re trying to basically through Pharma running clinical trials basically remove a lot of the useful supplements from supplement status via FDA regs?

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Moriarty's avatar

Yes I did.

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bio terry's avatar

Hallo Paul. I managed to get hold of berberine complex her in south africa but have done the fopmaps test for getting these headaches, since using it. Is it an indication there is something in these ingredients that can give me these headaches: Berberine hci 500mcg, chromium 20mcg, "probiotic blend" 100 mg (Probiotics are lacto acidophilus, bifidolongum, bifido bifidum and bifido lactis) , vit b1 @ 12.5mg, vit b6 @ 12.5mg, vit b12 @12.5mcg. To be taken 3 times per day with meals

As well as milk thistle 20mg

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Moriarty's avatar

Chromium probiotics and Berberine can also give you headaches, taking it with food may minimize the chances, but it is a common side effect. B1, B6 and B12 are not at the dosages necessary to give you headache, especially B1, one can take 1000 mg without almost any symptom or adverse-effect.

Milk Thistle can also give you headaches, but your dosages are "low"... so maybe the culprit is Berberine. Attempt to stick to it for a couple of weeks and see if there is an improvement.

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bio terry's avatar

Thank you. It is kind of hard but will try. I couldn't find anything on headaches as side effects on berberine, but i know chromium is a fat dissoving metal but i didn't remember headaches when i used it years back. Yes, and i forgot to mention i only used 1 berberine complex a day with meals, and the headaches last 3 days before starting to take them again, still 1 per day. Will it help if i take a teaspoon of olive oil with the meal, perhaps?

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bio terry's avatar

A question: i was under the impression someone i know who has been using metformin for a couple of months now, complained she us def getting constipated by it. I know they are calling it the wonder drug, but she is def sure that being by nature a constipated person, she is experiencing it since metformin use at an even worse scale. It seems that metformin has a good effect on the ackermansia probiotic, but not with her. She is also sensitive to oxalics and i don't know if her problem with metformin is more than just insulin resistance, being that she has neuralgia which she constantly have to baby by not eating foods high in metals as well as not too much calcium either, especially citrate type, which cause tremendous pain in the myelin sheath.

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Moriarty's avatar

Did she tried Metformin XR ? It usually much lighter in the gut with minimal gastric side effects. Push comes to shove she might just switch to Berberine if it is available/cheap where she lives, they are almost a 1 to 1 equal, borderline perfect analog.

Diet will also influence both the microbiome and constipation (sounds obvious I know). Neuralgia sometimes is a sign of thiamine deficiency.

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Dr Linda's avatar

Good to know!!

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Dr Linda's avatar

I was thinking several months at least not days

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rob's avatar

You can make yogurt with Akkermansia exactly same way as L.Reuteri (google how to) - I have done so successfully using 3 capsules of Pendulum as an initial starter. Drain the yogurt and put some whey aside to use as the next starter - or put into ice cube tray an freeze it all. one lump will work perfectly fine.

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bio terry's avatar

Interesting. Would love to try it. Can't seem to find akkermansia here, tried everywhere, even compounding pharmacy and way too expensive the pendelum product, but super idea.

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User's avatar
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Dec 16, 2022Edited
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Dr Linda's avatar

I started resistant starch as well. I have been keto and intermittently fast. I also do cryo therapy. Not sure what impact it might have on gut flora. But I feel so much better (I struggle with severe PTSD)

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bio terry's avatar

I remember i did a very low carb keto and ended up not being able to sleep for a long time because of lack of greenies which provide tryptophan for melatonin conversion. Being on isolated a farm i could luckily rely on nac which also have tryphto which helped me sleep, but i soon realize keto is NOT a one size fits all diet and has not been tested enough and still is a fad diet. After the keto it was 2 weeks before i was diagnosed with an ulcer. Had it treated profilactic with h. Oylori anti b, since the doc find high levels of h. Pylori in my blood, which meant absolutely nada for the gastro specialist and the endoscope showed an ulcer yes, big, but peptic. I ended up followed a good dietician diet according to blood group as well as for peptic ulcer, with extremely high vit d3 (5000) and vit- e which worked wonders. It is strange that i still tested low for vit d3 in south africa where we have such a lot of sunshine. Diet is like the modern mrna treatments they have for the last 3 years, one size never fits all...

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Dr Linda's avatar

I agree. One size dies not fit all. I was no advocating it as a solution. However, a diet of refined carbs and linoleic acid oil is a death wish.

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Moriarty's avatar

You literally explained why you had problems to sleep, why you had problems with keto, problems to have proper melatonin levels and tryptophan catabolism. Your gut.

Same situation I was for years (for a different reason). I do agree diet is not a one size fits all but the wider benefits of a low carb/keto diet is undeniable, we have populational data among many other qualities and types of data. It just don't fit well for some people, especially some with fucked up gut (me, you).

Fucked up gut will 100% affect how your body metabolize vitamin D. Plus other things such as bacterial infections, etc.

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Dr Linda's avatar

My digestion is remarkable with nattokinase, serrapeptase, and lumbrokinase. I alternate days. I am amazed. I had no idea that my digestion was sluggish or inefficient. Thank you

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Moriarty's avatar

One of the primary effects of the enzymes are a better digestion too, most people are not aware their digestion is slow until they experience "proper" digestion. Glad it was of benefit to you =D.

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bio terry's avatar

Yes. True, and all diabetics have a bad gut to start with.. since i am doing the 16/8 fasting i feel so much better. Hopefully it will not turn out too bad for me, since we are saturated with diabetics on my family side. The gastro specialist could not understand my crp levels whe ni had the peptic ulcer as well as my high boodsugar levels, but it cleared up the moment i followed the dieticians diet, and vit d3 as well as a good probiotic, but 4 times as much as daily recommendation rda (intestiflora).

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